Aberrant Wnt/β-catenin signaling has often been reported in different cancers, particularly
colorectal cancer (CRC), and this signaling cascade is central to carcinogenesis …

Several signaling pathways have been identified as important for developmental processes.
One of such important cascades is the Wnt/β‐catenin signaling pathway, which can regulate …

Abstract Background Circular RNA (circRNA), a subclass of non-coding RNA, plays a critical
role in cancer tumorigenesis and metastasis. It has been suggested that circRNA acts as a …

The evolutionarily conserved Wnt signaling pathway plays essential roles during embryonic
development and tissue homeostasis. Notably, comprehensive genetic studies in …

Controlled regulation of cell proliferation and differentiation is essential for embryonic
development and requires the coordinated regulation of cell–cell adhesion and gene …

The Wnt/β-catenin signaling pathway is a growth control pathway involved in various
biological processes as well as the development and progression of cancer. Colorectal …

Wnt/β-catenin and phosphatidylinositol-3-kinase/protein kinase B/mammalian target of
rapamycin complex 1 (PI3K/AKT/mTORC1) pathways both are critically involved in …

Several cellular signaling pathways are regulated by ADP-ribosylation, a posttranslational
modification catalyzed by members of the ARTD superfamily. Tankyrases are …

The products of the two mammalian Axin genes (Axin1 and its homologue Axin2) are
essential for the degradation of β catenin, a component of Wnt signalling that is frequently …

Colorectal cancer (CRC) is one of the most common carcinomas. Although great progress
has been made in recent years, CRC survival remains unsatisfactory due to high metastasis …