Two sides of the same coin: Protective versus pathogenic CD4+ resident memory T cells
AE Oja, RAW van Lier, P Hombrink - Science immunology, 2022 - science.org
The ability of the adaptive immune system to form memory is key to providing protection
against secondary infections. Resident memory T cells (TRM) are specialized T cell …
against secondary infections. Resident memory T cells (TRM) are specialized T cell …
Liver-resident memory T cells: life in lockdown
LJ Pallett, MK Maini - Seminars in Immunopathology, 2022 - Springer
A subset of memory T cells has been identified in the liver with a tissue-resident profile and
the capacity for long-term 'lockdown'. Here we review how they are retained in, and adapted …
the capacity for long-term 'lockdown'. Here we review how they are retained in, and adapted …
Psoriatic and rheumatoid arthritis joints differ in the composition of CD8+ tissue-resident memory T cell subsets
GAM Povoleri, LE Durham, EH Gray, S Lalnunhlimi… - Cell Reports, 2023 - cell.com
Summary CD69+ CD103+ tissue-resident memory T (T RM) cells are important drivers of
inflammation. To decipher their role in inflammatory arthritis, we apply single-cell, high …
inflammation. To decipher their role in inflammatory arthritis, we apply single-cell, high …
Tissue-resident immunity in the female and male reproductive tract
D Yüzen, PC Arck, K Thiele - Seminars in immunopathology, 2022 - Springer
The conception of how the immune system is organized has been significantly challenged
over the last years. It became evident that not all lymphocytes are mobile and recirculate …
over the last years. It became evident that not all lymphocytes are mobile and recirculate …
A novel human skin tissue model to study varicella-zoster virus and human cytomegalovirus
MG Lloyd, NA Smith, M Tighe, KL Travis, D Liu… - Journal of …, 2020 - Am Soc Microbiol
The herpesviruses varicella-zoster virus (VZV) and human cytomegalovirus (HCMV) are
endemic to humans. VZV causes varicella (chicken pox) and herpes zoster (shingles), while …
endemic to humans. VZV causes varicella (chicken pox) and herpes zoster (shingles), while …
Advancements in the characterization of tissue resident memory T cells in skin disease
The newly discovered subset of memory T cells, tissue resident memory T (TRM) cells,
reside in peripheral tissues for a long time, contributing to a rapid immune response and …
reside in peripheral tissues for a long time, contributing to a rapid immune response and …
Joint-specific memory, resident memory T cells and the rolling window of opportunity in arthritis
In rheumatoid arthritis, juvenile idiopathic arthritis and other forms of inflammatory arthritis,
the immune system targets certain joints but not others. The pattern of joints affected varies …
the immune system targets certain joints but not others. The pattern of joints affected varies …
Should I stay or should I go—Reconciling clashing perspectives on CD4+ tissue-resident memory T cells
FR Carbone, T Gebhardt - Science Immunology, 2019 - science.org
Should I stay or should I go—Reconciling clashing perspectives on CD4+ tissue-resident
memory T cells | Science Immunology news careers commentary Journals Science Science …
memory T cells | Science Immunology news careers commentary Journals Science Science …
Shared Mechanisms Govern HIV Transcriptional Suppression in Circulating CD103+ and Gut CD4+ T Cells
SA Yukl, S Khan, TH Chen, M Trapecar, F Wu… - Journal of …, 2020 - Am Soc Microbiol
Latent HIV infection is the main barrier to cure, and most HIV-infected cells reside in the gut,
where distinct but unknown mechanisms may promote viral latency. Transforming growth …
where distinct but unknown mechanisms may promote viral latency. Transforming growth …
Donor tissue-resident memory-like T and NK cells generate a transient peripheral chimerism in lung transplant recipients, potentially protective from chronic lung …
R Bellmàs-Sanz, AM Hitz, B Wiegmann, JF Kühne… - bioRxiv, 2023 - biorxiv.org
Lung transplantation (LTx) is the only definite treatment option of patients suffering from end-
stage lung disease. Long-term outcome is hampered by chronic allograft dysfunction …
stage lung disease. Long-term outcome is hampered by chronic allograft dysfunction …