[HTML][HTML] DNA methylation and brain structure and function across the life course: A systematic review
ENW Wheater, DQ Stoye, SR Cox, JM Wardlaw… - Neuroscience & …, 2020 - Elsevier
MRI has enhanced our capacity to understand variations in brain structure and function
conferred by the genome. We identified 60 studies that report associations between DNA …
conferred by the genome. We identified 60 studies that report associations between DNA …
Epigenetics of fragile X syndrome and fragile X‐related disorders
The fragile X mental retardation 1 gene (FMR 1)‐related disorder fragile X syndrome (FXS)
is the most common heritable form of cognitive impairment and the second most common …
is the most common heritable form of cognitive impairment and the second most common …
Role of DNA methylation in mediating genetic risk of psychiatric disorders
A Starnawska, D Demontis - Frontiers in Psychiatry, 2021 - frontiersin.org
Psychiatric disorders are common, complex, and heritable conditions estimated to be the
leading cause of disability worldwide. The last decade of research in genomics of psychiatry …
leading cause of disability worldwide. The last decade of research in genomics of psychiatry …
Oculomotor cognitive control abnormalities in Australian rules football players with a history of concussion
This study used oculomotor, cognitive, and multi-modal magnetic resonance imaging (MRI)
measures to assess for neurological abnormalities in current asymptomatic amateur …
measures to assess for neurological abnormalities in current asymptomatic amateur …
The Phenotypic Profile Associated With the FMR1 Premutation in Women: An Investigation of Clinical-Behavioral, Social-Cognitive, and Executive Abilities
The FMR1 gene in its premutation (PM) state has been linked to a range of clinical and
subclinical phenotypes among FMR1 PM carriers, including some subclinical traits …
subclinical phenotypes among FMR1 PM carriers, including some subclinical traits …
White matter microstructure, cognition, and molecular markers in fragile X premutation females
Objective: To examine the interrelationships between fragile X mental retardation 1 (FMR1)
mRNA and the FMR1 exon 1/intron 1 boundary methylation, white matter microstructure, and …
mRNA and the FMR1 exon 1/intron 1 boundary methylation, white matter microstructure, and …
Incomplete silencing of full mutation alleles in males with fragile X syndrome is associated with autistic features
EK Baker, M Arpone, SM Aliaga, L Bretherton… - Molecular autism, 2019 - Springer
Abstract Background Fragile X syndrome (FXS) is a common monogenic cause of
intellectual disability with autism features. While it is caused by loss of the FMR 1 product …
intellectual disability with autism features. While it is caused by loss of the FMR 1 product …
Molecular pathogenesis and peripheral monitoring of adult fragile X-associated syndromes
LM Valor, JC Morales, I Hervás-Corpión… - International Journal of …, 2021 - mdpi.com
Abnormal trinucleotide expansions cause rare disorders that compromise quality of life and,
in some cases, lifespan. In particular, the expansions of the CGG-repeats stretch at the 5' …
in some cases, lifespan. In particular, the expansions of the CGG-repeats stretch at the 5' …
Intragenic DNA methylation in buccal epithelial cells and intellectual functioning in a paediatric cohort of males with fragile X
Increased intragenic DNA methylation of the Fragile X Related Epigenetic Element 2
(FREE2) in blood has been correlated with lower intellectual functioning in females with …
(FREE2) in blood has been correlated with lower intellectual functioning in females with …
Long term verbal memory recall deficits in fragile X premutation females
Carriers of a FMR1 premutation allele (between 55 and 199 CGG repeats) are at risk of
developing a wide range of medical, psychiatric and cognitive disorders, including executive …
developing a wide range of medical, psychiatric and cognitive disorders, including executive …