Spät, András, and László Hunyady. Control of Aldosterone Secretion: A Model for
Convergence in Cellular Signaling Pathways. Physiol Rev 84: 489–539, 2004; …

Aldosterone, secreted by the adrenal zona glomerulosa, enhances sodium retention, thus
increasing blood volume and pressure. Excessive production of aldosterone results in high …

Cholesterol is required for maintenance of plasma membrane fluidity and integrity and for
many cellular functions. Cellular cholesterol can be obtained from lipoproteins in a selective …

Aldosterone is a steroid hormone synthesized in and secreted from the outer layer of the
adrenal cortex, the zona glomerulosa. Aldosterone is responsible for regulating sodium …

Diabetes is associated with significant changes in plasma concentrations of lipoproteins. We
tested the hypothesis that lipoproteins modulate the function and survival of insulin-secreting …

The scavenger receptor class B type I (SR-BI) is a 509-amino acid, 82kDa glycoprotein, with
two cytoplasmic C-and N-terminal domains separated by a large extracellular domain. The …

The steroidogenic tissues have a special requirement for cholesterol, which is used as a
substrate for steroid hormone biosynthesis. In many species this cholesterol is obtained from …

Aldosterone is a major mineralocorticoid steroid hormone secreted by glomerulosa cells in
the adrenal cortex. It regulates a variety of physiological responses including those to …

Polymorphic genes associated with Alzheimer's disease (see) delineate a clearly defined
pathway related to cerebral and peripheral cholesterol and lipoprotein homoeostasis. They …

Steroid hormones are synthesized using cholesterol as precursor, with a substantial portion
supplied by the selective uptake of lipoprotein-derived cholesteryl esters. Adrenals express …