Many retinal diseases, such as diabetic retinopathy, glaucoma, and age-related macular
(AMD) degeneration, are associated with elevated reactive oxygen species (ROS) levels …

Primary open angle glaucoma (POAG) is a complex progressive optic nerve neuropathy
triggered by both environmental and genetic risk factors. Several ocular tissues, including …

The APOE4 allele is the strongest genetic risk factor for late-onset Alzheimer's disease (AD).
The contribution of microglial APOE4 to AD pathogenesis is unknown, although APOE has …

Summary The apolipoprotein E4 (APOE4) allele is associated with an increased risk of
Alzheimer disease and a decreased risk of glaucoma, but the underlying mechanisms …

Glaucoma is the major cause of irreversible blindness worldwide. Primary open-angle
glaucoma (POAG), as the most prevalent form of glaucoma, is a complex inherited disorder …

The clinical and genetic relationships between Alzheimer's disease (AD) and glaucoma
remain obscure. The aim of this study was to determine the prevalence of open-angle …

Alzheimer's disease (AD) is the major cause of dementia in the world. Although the
entorhinal cortex and hippocampal complex are best known as the sites of early pathology …

Deficits in contrast sensitivity (CS) have been reported in Alzheimer's disease (AD).
However, the extent of these deficits in prodromal AD stages, including mild cognitive …

Glaucoma is a common, complex, heterogenous disease and it constitutes the major cause
of irreversible blindness worldwide. Primary open-angle glaucoma (POAG) is the most …

Evidence of a link between Alzheimer's disease (AD) and glaucoma has emerged from
studies showing that patients with AD may have a significantly increased rate of glaucoma …