[HTML][HTML] Oxidative stress and vascular dysfunction in the retina: Therapeutic strategies
Y Ruan, S Jiang, A Musayeva, A Gericke - Antioxidants, 2020 - mdpi.com
Many retinal diseases, such as diabetic retinopathy, glaucoma, and age-related macular
(AMD) degeneration, are associated with elevated reactive oxygen species (ROS) levels …
(AMD) degeneration, are associated with elevated reactive oxygen species (ROS) levels …
The vast complexity of primary open angle glaucoma: disease genes, risks, molecular mechanisms and pathobiology
SF Janssen, TGMF Gorgels, WD Ramdas… - Progress in retinal and …, 2013 - Elsevier
Primary open angle glaucoma (POAG) is a complex progressive optic nerve neuropathy
triggered by both environmental and genetic risk factors. Several ocular tissues, including …
triggered by both environmental and genetic risk factors. Several ocular tissues, including …
APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints
Z Yin, N Rosenzweig, KL Kleemann, X Zhang… - Nature …, 2023 - nature.com
The APOE4 allele is the strongest genetic risk factor for late-onset Alzheimer's disease (AD).
The contribution of microglial APOE4 to AD pathogenesis is unknown, although APOE has …
The contribution of microglial APOE4 to AD pathogenesis is unknown, although APOE has …
Apolipoprotein E4 impairs the response of neurodegenerative retinal microglia and prevents neuronal loss in glaucoma
Summary The apolipoprotein E4 (APOE4) allele is associated with an increased risk of
Alzheimer disease and a decreased risk of glaucoma, but the underlying mechanisms …
Alzheimer disease and a decreased risk of glaucoma, but the underlying mechanisms …
The genetics of primary open-angle glaucoma: a review
RR Allingham, Y Liu, DJ Rhee - Experimental eye research, 2009 - Elsevier
Glaucoma is the major cause of irreversible blindness worldwide. Primary open-angle
glaucoma (POAG), as the most prevalent form of glaucoma, is a complex inherited disorder …
glaucoma (POAG), as the most prevalent form of glaucoma, is a complex inherited disorder …
High frequency of open-angle glaucoma in Japanese patients with Alzheimer's disease
H Tamura, H Kawakami, T Kanamoto, T Kato… - Journal of the …, 2006 - Elsevier
The clinical and genetic relationships between Alzheimer's disease (AD) and glaucoma
remain obscure. The aim of this study was to determine the prevalence of open-angle …
remain obscure. The aim of this study was to determine the prevalence of open-angle …
Alzheimer's disease and retinal neurodegeneration
L Guo, J Duggan, MF Cordeiro - Current Alzheimer Research, 2010 - ingentaconnect.com
Alzheimer's disease (AD) is the major cause of dementia in the world. Although the
entorhinal cortex and hippocampal complex are best known as the sites of early pathology …
entorhinal cortex and hippocampal complex are best known as the sites of early pathology …
Visual contrast sensitivity in Alzheimer's disease, mild cognitive impairment, and older adults with cognitive complaints
Deficits in contrast sensitivity (CS) have been reported in Alzheimer's disease (AD).
However, the extent of these deficits in prodromal AD stages, including mild cognitive …
However, the extent of these deficits in prodromal AD stages, including mild cognitive …
[HTML][HTML] Current concepts on primary open-angle glaucoma genetics: a contribution to disease pathophysiology and future treatment
M Gemenetzi, Y Yang, AJ Lotery - Eye, 2012 - nature.com
Glaucoma is a common, complex, heterogenous disease and it constitutes the major cause
of irreversible blindness worldwide. Primary open-angle glaucoma (POAG) is the most …
of irreversible blindness worldwide. Primary open-angle glaucoma (POAG) is the most …
Alzheimer's disease and glaucoma: is there a causal relationship?
P Wostyn, K Audenaert, PP De Deyn - British Journal of …, 2009 - bjo.bmj.com
Evidence of a link between Alzheimer's disease (AD) and glaucoma has emerged from
studies showing that patients with AD may have a significantly increased rate of glaucoma …
studies showing that patients with AD may have a significantly increased rate of glaucoma …