Abstract Purpose of Review The following review discusses the therapeutic potential of
targeting the autonomic nervous system (ANS) for osteoarthritis (OA) treatment and …

Corticotropin-releasing hormone is a critical component of the hypothalamic–pituitary–
adrenal axis, which plays a major role in the body's immune response to stress. Mast cells …

Oxytocin is involved in pain transmission, although the detailed mechanism is not fully
understood. Here, we generate a transgenic rat line that expresses human muscarinic …

Objective By studying the changes of serum uric acid (SUA) in acute stage and remission
stage of gouty arthritis, we aimed to explore the relationship between the changes of SUA …

Arginine vasopressin (AVP) is a hypothalamic neurosecretory hormone well known as an
antidiuretic, and recently reported to be involved in pain modulation. The expression kinetics …

Osteoarthritis (OA) is a degenerative joint disease, characterized by infiltration of monocytes
into the synovial joint which promotes inflammation, stiffness, joint swelling, cartilage …

Background Osteoarthritis (OA) is the most common type of degenerative arthritis and affects
the entire joint, causing pain, joint inflammation, and cartilage damage. Various risk factors …

Oxytocin (OXT) was discovered in 1906 as a substance that promotes the pregnancy and
childbirth. It affects uterine contraction and lactation. Furthermore, as one of its physiological …

Osteoarthritis (OA) causes chronic joint pain and significantly impacts daily activities. Hence,
developing novel treatment options for OA has become an increasingly important area of …

Transgenic approaches have been applied to generate transgenic rats that express
exogenous genes in arginine vasopressin (AVP)‐and oxytocin (OXT)‐producing …