A translational neuroscience approach to understanding the development of social anxiety disorder and its pathophysiology

AS Fox, NH Kalin - American Journal of Psychiatry, 2014 - Am Psychiatric Assoc
This review brings together recent research from molecular, neural circuit, animal model,
and human studies to help understand the neurodevelopmental mechanisms underlying …

Dispositional negativity: An integrative psychological and neurobiological perspective.

AJ Shackman, DPM Tromp, MD Stockbridge… - Psychological …, 2016 - psycnet.apa.org
Dispositional negativity—the propensity to experience and express more frequent, intense,
or enduring negative affect—is a fundamental dimension of childhood temperament and …

Robust BOLD responses to faces but not to conditioned threat: challenging the amygdala's reputation in human fear and extinction learning

RM Visser, J Bathelt, HS Scholte… - Journal of …, 2021 - Soc Neuroscience
Most of our knowledge about human emotional memory comes from animal research. Based
on this work, the amygdala is often labeled the brain's “fear center”, but it is unclear to what …

Amygdala reactivity and anterior cingulate habituation predict posttraumatic stress disorder symptom maintenance after acute civilian trauma

JS Stevens, YJ Kim, IR Galatzer-Levy, R Reddy… - Biological …, 2017 - Elsevier
Background Studies suggest that exaggerated amygdala reactivity is a vulnerability factor for
posttraumatic stress disorder (PTSD); however, our understanding is limited by a paucity of …

[图书][B] Social anxiety: Clinical, developmental, and social perspectives

PM DiBartolo, SG Hofmann - 2014 - books.google.com
The third edition of Social Anxiety: Clinical, Developmental, and Social Perspectives
integrates examinations of social anxiety, shyness, and embarrassment with the research on …

[HTML][HTML] Patterns of brain activation when mothers view their own child and dog: An fMRI study

LE Stoeckel, LS Palley, RL Gollub, SM Niemi… - PloS one, 2014 - journals.plos.org
Neural substrates underlying the human-pet relationship are largely unknown. We
examined fMRI brain activation patterns as mothers viewed images of their own child and …

Neural substrates of childhood anxiety disorders: a review of neuroimaging findings

JU Blackford, DS Pine - Child and adolescent psychiatric clinics of North …, 2012 - Elsevier
Anxiety disorders are the most common group of childhood psychiatric disorders, with
almost one in three children having suffered from an anxiety disorder at some point during …

Failure to filter: Anxious individuals show inefficient gating of threat from working memory

DM Stout, AJ Shackman, CL Larson - Frontiers in human …, 2013 - frontiersin.org
Dispositional anxiety is a well-established risk factor for the development of psychiatric
disorders along the internalizing spectrum, including anxiety and depression. Importantly …

Cortico-limbic interactions mediate adaptive and maladaptive responses relevant to psychopathology

R Kovner, JA Oler, NH Kalin - American Journal of Psychiatry, 2019 - Am Psychiatric Assoc
Cortico-limbic circuits provide a substrate for adaptive behavioral and emotional responses.
However, dysfunction of these circuits can result in maladaptive responses that are …

[HTML][HTML] Amygdala habituation: a reliable fMRI phenotype

MM Plichta, O Grimm, K Morgen, D Mier, C Sauer… - NeuroImage, 2014 - Elsevier
Amygdala function is of high interest for cognitive, social and psychiatric neuroscience,
emphasizing the need for reliable assessments in humans. Previous work has indicated …