Human adenoviruses (HAdVs) are an important cause of infections in both
immunocompetent and immunocompromised individuals, and they continue to provide …

Cytogenetics of Bone and Soft Tissue Tumors [1]. In view of the remarkable developments in
this field since 1994, both in the cytogenetic and particularly in the molecular genetic …

Chronic infection with the hepatitis B virus (HBV) is a major risk factor for development of
hepatocellular carcinoma (HCC). The pathogenesis of cancer in HBV infection has been …

As discussed in detail in other chapters of this review, chronic hepatitis B (HBV) infection is a
major risk factor for hepatocellular carcinoma (HCC). Most HCCs complicate the evolution of …

Hepatocellular carcinoma (HCC) is the most common histological form of primary liver
cancer, the tumor cells having retained features of hepatocytic differentiation. It is important …

According to classical concepts of viral oncogenesis, the persistence of virus-specific
oncogenes is required to maintain the transformed cellular phenotype. In contrast, the “hit …

The presence of human herpesvirus-8 DNA sequences, as well as an overexpression of
human interleukin-6 and human cyclin D1 in myofibroblastic cells of inflammatory …

Multivalent dengue vaccines now in late stage development pose unique vaccine safety
challenges in that primary or secondary vaccine failures might place vaccines at risk to …

EFT is defined by the expression of ews/ets fusion genes. The type of the fusion transcript
impacts on the clinical biology. EFT requires risk adapted treatment. A risk-adapted …

Background Malignant transformation requires the accumulation of multiple genetic
alterations such as chromosomal abnormalities, oncogene activation, loss of tumor …