[HTML][HTML] Pharmacological treatment of chemotherapy-induced neuropathic pain: PPARγ agonists as a promising tool

NLM Quintão, JR Santin, LC Stoeberl… - Frontiers in …, 2019 - frontiersin.org
Chemotherapy-induced neuropathic pain (CINP) is one of the most severe side effects of
anticancer agents, such as platinum-and taxanes-derived drugs (oxaliplatin, cisplatin …

Methods for in vivo studies in rodents of chemotherapy induced peripheral neuropathy

J Bruna, P Alberti, A Calls-Cobos, M Caillaud… - Experimental …, 2020 - Elsevier
Peripheral neuropathy is one of the most common, dose limiting, and long-lasting disabling
adverse events of chemotherapy treatment. Unfortunately, no treatment has proven efficacy …

Effects of Yulin Tong Bu formula on modulating gut microbiota and fecal metabolite interactions in mice with polycystic ovary syndrome

YN Su, MJ Wang, JP Yang, XL Wu, M Xia… - Frontiers in …, 2023 - frontiersin.org
Background Polycystic ovarian syndrome (PCOS) is a common endocrine disorder
characterized by hyperandrogenism, ovarian dysfunction and polycystic ovarian …

[HTML][HTML] Suppression of TRPV1/TRPM8/P2Y nociceptors by withametelin via downregulating MAPK signaling in mouse model of vincristine-induced neuropathic pain

A Khan, B Shal, AU Khan, R Ullah, MW Baig… - International journal of …, 2021 - mdpi.com
Vincristine (VCR) is a widely used chemotherapy drug that induced peripheral painful
neuropathy. Yet, it still lacks an ideal therapeutic strategy. The transient receptor potential …

[HTML][HTML] Mitoquinone alleviates vincristine-induced neuropathic pain through inhibiting oxidative stress and apoptosis via the improvement of mitochondrial …

XJ Chen, L Wang, XY Song - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Chemotherapy drugs such as vincristine (Vin) could cause neuropathic pain. However, it is
still lack of ideal therapeutic strategy to treat it. Mitochondrial dysfunction has been involved …

Neuroprotective mechanism of Ajugarin-I against Vincristine-Induced neuropathic pain via regulation of Nrf2/NF-κB and Bcl2 signalling

A Khan, B Shal, AU Khan, KU Shah, SS Zahra… - International …, 2023 - Elsevier
Vincristine (VCR) is a well-known chemotherapeutic agent that frequently triggers
neuropathic pain. Ajugarin-I (Aju-I) isolated from Ajuga bracteosa exerts antioxidant, anti …

[HTML][HTML] Modular characteristics and mechanism of action of herbs for endometriosis treatment in Chinese medicine: a data mining and network pharmacology–based …

W Zheng, J Wu, J Gu, H Weng, J Wang… - Frontiers in …, 2020 - frontiersin.org
Endometriosis is a common benign disease in women of reproductive age. It has been
defined as a disorder characterized by inflammation, compromised immunity, hormone …

[HTML][HTML] Biomarkers of chemotherapy-induced peripheral neuropathy: Current status and future directions

RL Rodwin, NZ Siddiq, BE Ehrlich… - Frontiers in Pain …, 2022 - frontiersin.org
Chemotherapy induced peripheral neuropathy (CIPN) is an often severe and debilitating
complication of multiple chemotherapeutic agents that can affect patients of all ages, across …

Through its powerful antioxidative properties, l-theanine ameliorates vincristine-induced neuropathy in rats

CC Yang, MH Wang, HS Soung, HC Tseng, FH Lin… - Antioxidants, 2023 - mdpi.com
L-theanine (LT), which is a major amino acid found in green tea, was shown to alleviate
Vincristine (VCR)-induced peripheral neuropathy and associated neuronal functional …

[HTML][HTML] Cardiovascular toxicity induced by chronic vincristine treatment

E Herradón, C González, A González… - Frontiers in …, 2021 - frontiersin.org
Vincristine is an effective anticancer agent for treating leukemias, lymphomas, and other
solid tumors. Vincristine's better-known severe side effects include bone marrow depression …