The gastrointestinal tract is a specialized organ in which dynamic interactions between host
cells and the complex environment occur in addition to food digestion. Together with the …

This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …

Butyrate, one of the SCFA, promotes the development of the intestinal barrier. However, the
molecular mechanisms underlying the butyrate regulation of the intestinal barrier are …

Short-chain fatty acids (SCFAs) are carboxylic acids produced as a result of gut microbial
anaerobic fermentation. They activate signaling cascades, acting as ligands of G-protein …

Tight junctions (TJs) regulate the passage of ions and molecules through the paracellular
pathway in epithelial and endothelial cells. TJs are highly dynamic structures whose degree …

Excessive heat exposure reduces intestinal integrity and post-absorptive energetics that can
inhibit wellbeing and be fatal. Therefore, our objectives were to examine how acute heat …

Agrowing body of evidence indicates that endotox-emia is closely associated with alcoholic
liver disease (ALD). Endotoxins stimulate different cells in the liver releasing cytokines …

Production of short-chain fatty acids (SCFA) in the intestinal lumen may play an important
role in the maintenance of the intestinal barrier. However, overproduction/accumulation of …

The gastrointestinal (GI) tract can play a critical role in the development of pathologies
associated with overeating, overweight and obesity. We previously observed that …

Probiotics are beneficial bacteria present in various dietary components and many of these
colonize in the human and animal intestine. In the gut probiotics help the host by assisting in …