Lactoferrin from milk: Nutraceutical and pharmacological properties
Lactoferrin is an iron-binding protein present in large quantities in colostrum and in breast
milk, in external secretions and in polymorphonuclear leukocytes. Lactoferrin's main function …
milk, in external secretions and in polymorphonuclear leukocytes. Lactoferrin's main function …
Lactoferrin: A glycoprotein involved in immunomodulation, anticancer, and antimicrobial processes
Q Rascón-Cruz, EA Espinoza-Sánchez… - Molecules, 2021 - mdpi.com
Lactoferrin is an iron binding glycoprotein with multiple roles in the body. Its participation in
apoptotic processes in cancer cells, its ability to modulate various reactions of the immune …
apoptotic processes in cancer cells, its ability to modulate various reactions of the immune …
Synthetic antibiotic derived from sequences encrypted in a protein from human plasma
Encrypted peptides have been recently found in the human proteome and represent a
potential class of antibiotics. Here we report three peptides derived from the human …
potential class of antibiotics. Here we report three peptides derived from the human …
Lactoferrin as a nutraceutical protein from milk, an overview
BF Iglesias-Figueroa, EA Espinoza-Sánchez… - International dairy …, 2019 - Elsevier
Lactoferrin, a non-haeme iron-binding glycoprotein, known as the red fraction of milk, has
been recently called a nutraceutical protein. Lactoferrin protein participates in some …
been recently called a nutraceutical protein. Lactoferrin protein participates in some …
ALA‐A2 Is a Novel Anticancer Peptide Inspired by Alpha‐Lactalbumin: A Discovery from a Computational Peptide Library, In Silico Anticancer Peptide Screening and …
T Lerksuthirat, P On‐yam, S Chitphuk… - Global …, 2023 - Wiley Online Library
Anticancer peptides (ACPs) are rising as a new strategy for cancer therapy. However,
traditional laboratory screening to find and identify novel ACPs from hundreds to thousands …
traditional laboratory screening to find and identify novel ACPs from hundreds to thousands …
Neurokinin-1 receptor is an effective target for treating leukemia by inducing oxidative stress through mitochondrial calcium overload
C Ge, H Huang, F Huang, T Yang… - Proceedings of the …, 2019 - National Acad Sciences
Substance P (SP) regulates multiple biological processes through its high-affinity neurokinin-
1 receptor (NK-1R). While the SP/NK-1R signaling axis is involved in the pathogenesis of …
1 receptor (NK-1R). While the SP/NK-1R signaling axis is involved in the pathogenesis of …
The potential use of peptides in cancer treatment
Conventional chemotherapeutic drugs have significant limitations. For example, tumors may
develop resistance, cancers may relapse after treatment, and the drugs may induce …
develop resistance, cancers may relapse after treatment, and the drugs may induce …
Insights into the antimicrobial activity and cytotoxicity of engineered α-helical peptide amphiphiles
Z Ma, J Yang, J Han, L Gao, H Liu, Z Lu… - Journal of Medicinal …, 2016 - ACS Publications
Antimicrobial peptides (AMPs) have gained increasing attention, as they can overcome
recurring microbial invasions. However, their poor antimicrobial activity and potential …
recurring microbial invasions. However, their poor antimicrobial activity and potential …
Cathelicidin hCAP18/LL-37 promotes cell proliferation and suppresses antitumor activity of 1,25(OH)2D3 in hepatocellular carcinoma
H Zhang, J Zhen, R Zhang, Y Wanyan, K Liu… - Cell death …, 2022 - nature.com
Abstract Cathelicidin hCAP18/LL-37 can resist infection from various pathogens and is an
essential component of the human immune system. Accumulating evidence has indicated …
essential component of the human immune system. Accumulating evidence has indicated …
Nisin ZP, an Antimicrobial Peptide, Induces Cell Death and Inhibits Non-Small Cell Lung Cancer (NSCLC) Progression in vitro in 2D and 3D Cell Culture
Lung cancer is the leading cause of cancer deaths globally with most of the reported cases
(> 85%) associated with non-small cell lung cancer (NSCLC). Current therapies have …
(> 85%) associated with non-small cell lung cancer (NSCLC). Current therapies have …