Human eukaryotic prohibitin (prohibitin-1 and prohibitin-2) is a membrane protein with
different cellular localizations. It is involved in multiple cellular functions, including energy …

Gliomas are invasive brain tumors characterized by high rates of recurrence and mortality.
Glioblastoma (GBM), a grade IV brain tumor, is known for its heterogenicity and its …

Abstract Background Cancer stem cells (CSCs), which are involved in cancer initiation and
metastasis, could potentially release exosomes that mediate cellular communication by …

Background Damaged endothelial cells and downregulated osteogenic ability are two key
pathogenic mechanisms of glucocorticoid (GC)-induced osteonecrosis of the femoral head …

OBJECTIVE: To investigate the specific role of microRNA-26 (miRNA-26a) in a rat model of
cerebral ischemic stroke and the underlying mechanism. MATERIALS AND METHODS: A rat …

MicroRNAs (miRNAs) are non-coding RNAs with only 20–22 nucleic acids that inhibit gene
transcription and translation by binding to mRNA. MiRNAs have a diverse set of target genes …

Background. The microglia cell transfer has been shown to play a protective role in ischemic
stroke. Microglia cells may play this nerve-protective role via the promotion of angiogenesis …

Prohibitin (PHB) was originally isolated and characterized as an anti-proliferative gene in rat
liver. The evolutionarily conserved PHB gene encodes two human protein isoforms with …

Very large bone defects significantly diminish the vascular, blood, and nutrient supply to the
injured site, reducing the bone's ability to self-regenerate and complicating treatment …

Glioblastoma (GB) is a highly aggressive cancer of the central nervous system, occurring in
the brain or spinal cord. Many factors such as angiogenesis are associated with GB …