Translationally controlled tumor protein (TCTP), also called histamine releasing factor (HRF)
or fortilin, is a multifunctional protein present in almost all eukaryotic organisms. TCTP is …

The translationally controlled tumor protein (TCTP) is a highly conserved protein present in
eukaryotic organisms. This protein, located both in the cytoplasmic and the nucleus, is …

Glycosylation with O-linked β-N-acetylglucosamine (O-GlcNAc) is one of the protein
glycosylations affecting various intracellular events. However, the role of O-GlcNAcylation in …

Defective glucose-stimulated insulin secretion (GSIS) and β-cell senescence are hallmarks
in diabetes. The mitochondrial enzyme pyruvate carboxylase (PC) has been shown to …

The endoplasmic reticulum, the cytoplasmic organelle that matures a massive amount of
nascent secretory polypeptides, is particularly sensitive to stress. Endoplasmic reticulum …

Abstract The Translational Controlled Tumour Protein TCTP (gene symbol TPT1, also called
P21, P23, Q23, fortilin or histamine-releasing factor, HRF) is a highly conserved protein …

Heat shock protein 27 (Hsp27) is highly overexpressed in castration-resistant prostate
cancer (CRPC) and an antisense inhibitor (OGX-427) is currently in phase II clinical trials. In …

Long-term exposure of beta cells to saturated fatty acids impairs insulin secretion and
increases apoptosis. In contrast, unsaturated fatty acids protect beta-cells from the long-term …

The translationally controlled tumor protein (TCTP) displays growth-promoting and
antiapoptotic properties. To gain information on the role of TCTP in cancer disease, we …

Purpose Prolactinoma is the most commonly seen secretory tumor of pituitary glands, which
accounts for approximately up to 40% of total pituitary adenomas. Due to its high drug …