Roadmap: helium ion therapy

A Mairani, S Mein, E Blakely, J Debus… - Physics in Medicine …, 2022 - iopscience.iop.org
Helium ion beam therapy for the treatment of cancer was one of several developed and
studied particle treatments in the 1950s, leading to clinical trials beginning in 1975 at the …

Fraction optimization for hybrid proton‐photon treatment planning

W Li, W Zhang, Y Lin, RC Chen, H Gao - Medical physics, 2023 - Wiley Online Library
Background Hybrid proton‐photon radiotherapy (RT) can provide better plan quality than
proton or photon only RT, in terms of robustness of target coverage and sparing of organs‐at …

A novel stochastic optimization method for handling misalignments of proton and photon doses in combined treatments

S Fabiano, N Torelli, D Papp… - Physics in Medicine & …, 2022 - iopscience.iop.org
Objective. Combined proton–photon treatments, where most fractions are delivered with
photons and only a few are delivered with protons, may represent a practical approach to …

Combined BNCT-CIRT treatment planning for glioblastoma using the effect-based optimization

Y Han, C Geng, S Altieri, S Bortolussi… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. Boron neutron capture therapy (BNCT) and carbon ion radiotherapy (CIRT) are
emerging treatment modalities for glioblastoma. In this study, we investigated the …

Post-irradiation recovery of B14-150 fibrosarcoma cells after combined irradiation with low and high linear energy transfer

EV Koryakina, VI Potetnya, MV Troshina… - Bulletin of Experimental …, 2022 - Springer
The use of radiation with low and high linear energy transfer (LET) in the same treatment
regimen is promising in terms of increasing the efficiency and reducing the severity of …

Пострадиационное восстановление клеток фибросаркомы B14-150 после сочетанного воздействия излучением с низкой и высокой линейной передачей …

ЕВ Корякина, ВИ Потетня, МВ Трошина… - … биологии и медицины, 2022 - elibrary.ru
Использование излучения с низкими и высокими значениями линейной передачи
энергии (ЛПЭ) в одной схеме лечения перспективно с точки зрения повышения …

Carbon Ion Irradiation Downregulates Notch Signaling in Glioma Cell Lines, Impacting Cell Migration and Spheroid Formation

V Kumar, M Vashishta, L Kong, JJ Lu, X Wu… - Cells, 2022 - mdpi.com
Photon-based radiotherapy upregulates Notch signaling in cancer, leading to the acquisition
of the stem cell phenotype and induction of invasion/migration, which contributes to the …

Combined Photon-Carbon ion Radiotherapy Treatment Planning

ABA Bennan - 2022 - archiv.ub.uni-heidelberg.de
Carbon ion therapy is a promising treatment modality that is not widely accessible to patients
due to limited resources and a high cost of treatment. Therefore, it is necessary to consider …

[PDF][PDF] Carbon Ion Irradiation Downregulates Notch Signaling in Glioma Cell Lines, Impacting Cell Migration and Spheroid Formation. Cells 2022, 11, 3354

V Kumar, M Vashishta, L Kong, JJ Lu, X Wu… - 2022 - academia.edu
Photon-based radiotherapy upregulates Notch signaling in cancer, leading to the acquisition
of the stem cell phenotype and induction of invasion/migration, which contributes to the …

[PDF][PDF] Part C: Clinical Perspectives

H Paganetti - Roadmap: helium ion therapy - indico.cern.ch
The primary mission of clinical medical physics in radiation oncology is to ensure that the
planned dose is correctly delivered to the patient. More specifically, the patient must receive …