Protein glycosylation has a huge impact on biological processes in all domains of life. The
type of glycan present on a recombinant glycoprotein depends on protein intrinsic features …

Plants are increasingly used for the production of high-quality biological molecules for use
as pharmaceuticals and biomaterials in industry. Plants have proved that they can produce …

Immune checkpoint inhibitors (ICIs) have achieved huge clinical success. However, many
still have limited response rates, and are prohibitively costly. There is a need for effective …

Control over glycosylation is an important quality parameter in recombinant protein
production. Here, we demonstrate the generation of a marker‐free genome edited Nicotiana …

The recent SARS‐CoV‐2 pandemic has taught the world a costly lesson about the
devastating consequences of viral disease outbreaks but also, the remarkable impact of …

Introduction: Prolyl-4-hydroxylases (P4H) catalyse the irreversible conversion of proline to
hydroxyproline, constituting a common posttranslational modification of proteins found in …

Highlights•Plant-based expression systems are promising for producing recombinant N-
linked glycoproteins.•Review explores plant glycoengineering history and recent advances …

Introduction The Golgi apparatus of plants is the central cellular organelle for glycan
processing and polysaccharide biosynthesis. These essential processes are catalyzed by a …

For several decades, a plant‐based expression system has been proposed as an alternative
platform for the production of biopharmaceuticals including therapeutic monoclonal …