Candidiasis has increased substantially worldwide over recent decades and is a significant
cause of morbidity and mortality, especially among critically ill patients. Diabetes mellitus …

Patients with suppressed immunity are at the highest risk for hospital-acquired infections.
Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial …

Despite abundant research in the field of antifungal drug discovery, fungal infections remain
a significant healthcare burden. There is an emerging need for the development of novel …

Candida parapsilosis is the second most common Candida species isolated in Asia,
Southern Europe, and Latin America and is often involved in invasive infections that …

Recently, the dramatic emergence of antimicrobial resistance has received attention from
World Health Organization. Synthetic antimicrobial peptides (SAMPs) are considered new …

In recent years, the demand for novel antifungal therapies has increased several-folds due
to its potential to treat severe biofilm-associated infections. Biofilms are made by the sessile …

Context Candida-related infections are nowadays a serious Public Health Problem
emerging multidrug-resistant strains. Candida biofilm also leads bloodstream infections to …

Introduction The term invasive candidiasis (IC) refers to both bloodstream and deep-seated
invasive infections, such as peritonitis, caused by Candida species. Several guidelines on …

Candida is the most implicated fungal pathogen in the clinical setting. Several factors play
important roles in the pathogenesis of Candida spp. Multiple transcriptional circuits …

Role of biofilm in disease development and enhance tolerance to antifungal drugs among
Candida species has necessitated search for new anti-fungal treatment strategy …