Despite nearly three decades of advances in the management of rheumatoid arthritis (RA), a
substantial minority of patients are exposed to multiple DMARDs without necessarily …

Low back pain is the leading cause for years lived in disability. Most people with acute low
back pain improve rapidly, but 4% to 25% of patients become chronic. Since the previous …

Low back pain (LBP) is one of the major disabling health conditions among older adults
aged 60 years or older. While most causes of LBP among older adults are non-specific and …

Pain and substance use are highly prevalent and co-occurring conditions that continue to
garner increasing clinical and empirical interest. Although nicotine and tobacco, alcohol …

Tobacco addiction and chronic pain represent 2 highly prevalent and comorbid conditions
that engender substantial burdens upon individuals and systems. Interrelations between …

Chronic pain is common and complex and has a large impact on individuals and society.
Good epidemiological pain data provide key information on the use of resources (both in …

A variety of factors may be involved in the development and course of musculoskeletal
(MSK) pain. We undertook a systematic review with meta-analysis to synthesize and …

Although animal models have consistently demonstrated acute pain inhibitory effects of
nicotine and tobacco, human experimental studies have yielded mixed results. The main …

Introduction Ingestion of nicotine by smoking, vaping, or other means elicits various effects
including reward, antinociception, and aversion due to irritation, bitter taste, and unpleasant …

Tobacco smoking is associated with adverse health effects, and its relationship to pain is
complex. The longitudinal effect of smoking on patients attending a tertiary pain …