Nearly 40 years have elapsed since the invention of the PCR, with its extremely sensitive
and specific ability to detect nucleic acids via in vitro enzyme-mediated amplification. In turn …

Syndromic panels have allowed clinical microbiology laboratories to rapidly identify
bacteria, viruses, fungi, and parasites and are now fully integrated into many clinical …

Advanced microbiology technologies such as multiplex molecular assays (ie syndromic
diagnostic tests) are a novel approach to the rapid diagnosis of common infectious diseases …

Infectious diarrhoea contributes to high morbidity and mortality in young children from sub-
Saharan Africa. The aim of this study was to assess the prevalence of single and multiple …

Since the discovery of norovirus in 1972 as a cause of what was contemporarily known as
acute infectious non-bacterial gastroenteritis, scientific understanding of the viral …

Abstract Background Rapid diagnostic tests (RDTs) for infectious diseases, with a
turnaround time of less than 2 hours, are promising tools that could improve patient care …

Blood cultures have been the staple of clinical microbiology laboratories for well over half a
century, but gaps remain in our ability to identify the causative agent in patients presenting …

In acute gastroenteritis (AGE), identification of the infectious agent is important for patient
management. Since symptoms do not reliably identify the agent, microbiological diagnostics …

Background and aims Gastrointestinal infections have been linked to changes in the
composition and function of gut microbiome and development of inflammatory bowel …

Background: Infectious diarrhoea is a significant cause of morbidity worldwide. Culture and
microscopy are time-consuming and have a low yield. New rapid molecular methods such …