Effectiveness of BNT162b2 and CoronaVac in children and adolescents against SARS-CoV-2 infection during Omicron BA. 2 wave in Hong Kong

D Leung, JS Rosa Duque, KM Yip, HK So… - Communications …, 2023 - nature.com
Abstract Background The SARS-CoV-2 Omicron BA. 2 subvariant replaced BA. 1 globally in
early 2022, and caused an unprecedented tsunami of cases in Hong Kong, resulting in the …

Hesitancy, reactogenicity and immunogenicity of the mRNA and whole-virus inactivated Covid-19 vaccines in pediatric neuromuscular diseases

MKL Yu, SHS Chan, S Cheng, D Leung… - Human Vaccines & …, 2023 - Taylor & Francis
The mRNA-based BNT162b2 and inactivated whole-virus CoronaVac are two widely used
COVID-19 vaccines that confer immune protection to healthy individuals. However …

SARS‐CoV‐2 reinfection broadens the antibody responses and promotes the phenotypic differentiation of virus‐specific memory T cells in adolescents

XJ Zhao, XL Liu, HJ Gu, T Liu, DY Li… - Journal of medical …, 2024 - Wiley Online Library
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
Omicron subvariants raises concerns regarding the effectiveness of immunity acquired from …

Diagnosis, treatment and prevention of severe acute respiratory syndrome coronavirus 2 infection in children: experts' consensus statement updated for the Omicron …

RM Jiang, ZD Xie, Y Jiang, XX Lu, RM Jin… - World Journal of …, 2024 - Springer
It has been more than 3 years since the novel coronavirus (SARS‑CoV‑2) pandemic raged
globally. The coronavirus disease 2019 (COVID‑19) has greatly influenced human society …

Superior antibody and membrane protein-specific T-cell responses to CoronaVac by intradermal versus intramuscular routes in adolescents

JS Rosa Duque, SMS Cheng, CA Cohen… - World Journal of …, 2024 - Springer
Background Optimising the immunogenicity of COVID-19 vaccines to improve their
protection against disease is necessary. Fractional dosing by intradermal (ID) administration …

Immunogenicity of coronavirus disease 2019 vaccines in children: A review with ChatGPT

D Leung, J Rosa Duque, W Tu, YL Lau - Pediatric Discovery, 2023 - Wiley Online Library
SARS‐CoV‐2 causes millions of infection cases and coronavirus disease 2019 (COVID‐19)‐
related deaths worldwide. In addition to acute illnesses, children and adolescents suffer from …

[HTML][HTML] Live virus neutralizing antibodies against pre and post Omicron strains in food and retail workers in Québec, Canada

H Rabezanahary, C Gilbert, K Santerre, M Scarrone… - Heliyon, 2024 - cell.com
Background Measuring the ability of SARS-CoV-2 antibodies to neutralize live viruses
remains an effective approach to quantify the level of protection of individuals. We assessed …

Humoral and cellular immunogenicity and safety of 3 doses of CoronaVac and BNT162b2 in young children and adolescents with kidney diseases

D Leung, EY Chan, X Mu, JS Rosa Duque, SMS Cheng… - medRxiv, 2022 - medrxiv.org
Background Patients with kidney diseases are at risk of severe complications from COVID-
19, yet little is known about the effectiveness of COVID-19 vaccines in children and …

Interferon-γ Release Assay in the Assessment of Cellular Immunity—A Single-Centre Experience with mRNA SARS-CoV-2 Vaccine in Patients with Juvenile Idiopathic …

K Kapten, K Orczyk, A Maeser… - Journal of Clinical …, 2024 - mdpi.com
Background: As the SARS-CoV-2 virus remains one of the main causes of severe respiratory
system infections, the Food and Drug Administration strongly advises the continuation of …

Superior antibody and membrane protein-specific T-cell responses to CoronaVac by intradermal versus intramuscular routes in adolescents

S Cheng, CA Cohen, D Leung, X Wang, X Mu… - World Journal of …, 2023 - hub.hku.hk
Background: Optimising the immunogenicity of COVID-19 vaccines to improve their
protection against disease is necessary. Fractional dosing by intradermal (ID) administration …