Drug resistance mechanisms and drug susceptibility testing for tuberculosis
Tuberculosis (TB) caused by Mycobacterium tuberculosis (MTB) is the deadliest infectious
disease and the associated global threat has worsened with the emergence of drug …
disease and the associated global threat has worsened with the emergence of drug …
Molecular Diagnostics for Mycobacterium tuberculosis Infection
Resistance to antimycobacterial drugs is a major barrier to effective treatment of
Mycobacterium tuberculosis infection. Molecular diagnostic techniques based on the …
Mycobacterium tuberculosis infection. Molecular diagnostic techniques based on the …
[HTML][HTML] Detection of mutations in the rpoB gene of rifampicin-resistant Mycobacterium tuberculosis strains inhibiting wild type probe hybridization in the MTBDR plus …
P Sinha, GN Srivastava, R Tripathi, MN Mishra… - BMC microbiology, 2020 - Springer
Background The potential of genetic testing for rapid and accurate diagnosis of drug-
resistant Mycobacterium tuberculosis strains is vital for efficient treatment and reduction in …
resistant Mycobacterium tuberculosis strains is vital for efficient treatment and reduction in …
Profile and frequency of mutations conferring drug-resistant tuberculosis in the central, Southeastern and Eastern Ethiopia
Purpose Advances in molecular tools that assess genes harboring drug resistance
mutations have greatly improved the detection and treatment of drug-resistant tuberculosis …
mutations have greatly improved the detection and treatment of drug-resistant tuberculosis …
Some Synonymous and Nonsynonymous gyrA Mutations in Mycobacterium tuberculosis Lead to Systematic False-Positive Fluoroquinolone Resistance Results with the Hain …
In this study, using the Hain GenoType MTBDR sl assays (versions 1 and 2), we found that
some nonsynonymous and synonymous mutations in gyrA in Mycobacterium tuberculosis …
some nonsynonymous and synonymous mutations in gyrA in Mycobacterium tuberculosis …
Multiplex detection of extensively drug resistant tuberculosis using binary deoxyribozyme sensors
HN Bengtson, S Homolka, S Niemann, AJ Reis… - Biosensors and …, 2017 - Elsevier
Current diagnostic tools for Mycobacterium tuberculosis (Mtb) have many disadvantages
including low sensitivity, slow turnaround times, or high cost. Accurate, easy to use, and …
including low sensitivity, slow turnaround times, or high cost. Accurate, easy to use, and …
Evolution of phenotypic and molecular drug susceptibility testing
DM Cirillo, P Miotto, E Tortoli - … tuberculosis complex: its role in biology …, 2017 - Springer
Abstract Drug Resistant Tuberculosis (DRTB) is an emerging problem world-wide. In order
to control the disease and decrease the number of cases overtime a prompt diagnosis …
to control the disease and decrease the number of cases overtime a prompt diagnosis …
[HTML][HTML] Patterns and profiles of drug resistance-conferring mutations in Mycobacterium tuberculosis genotypes isolated from tuberculosis-suspected attendees of …
Purpose This study examined the patterns and frequency of genetic changes responsible for
resistance to first-line (rifampicin and isoniazid), fluoroquinolones, and second-line …
resistance to first-line (rifampicin and isoniazid), fluoroquinolones, and second-line …
[HTML][HTML] Diagnostic accuracy and usefulness of the Genotype MTBDRplus assay in diagnosing multidrug-resistant tuberculosis in Cameroon: A cross-sectional study
Background Drug-resistant tuberculosis, especially multidrug-resistant tuberculosis (MDR-
TB), is a major public health problem. Effective management of MDR-TB relies on accurate …
TB), is a major public health problem. Effective management of MDR-TB relies on accurate …
Systematic evaluation of line probe assays for the diagnosis of tuberculosis and drug-resistant tuberculosis
M Lin, YW Chen, YR Li, LJ Long, LY Qi, TT Cui… - Clinica Chimica …, 2022 - Elsevier
Abstract Background Line probe assays (LPAs) are PCR-based assays used for the rapid
diagnosis of Mycobacterium tuberculosis (MTB) and drug-resistant tuberculosis (DR-TB). But …
diagnosis of Mycobacterium tuberculosis (MTB) and drug-resistant tuberculosis (DR-TB). But …