In-vivo and ex-vivo tissue analysis through hyperspectral imaging techniques: revealing the invisible features of cancer

M Halicek, H Fabelo, S Ortega, GM Callico, B Fei - Cancers, 2019 - mdpi.com
In contrast to conventional optical imaging modalities, hyperspectral imaging (HSI) is able to
capture much more information from a certain scene, both within and beyond the visual …

[HTML][HTML] Niche preclinical and clinical applications of photoacoustic imaging with endogenous contrast

S John, S Hester, M Basij, A Paul, M Xavierselvan… - Photoacoustics, 2023 - Elsevier
In the past decade, photoacoustic (PA) imaging has attracted a great deal of popularity as an
emergent diagnostic technology owing to its successful demonstration in both preclinical …

Detection of collagens by multispectral optoacoustic tomography as an imaging biomarker for Duchenne muscular dystrophy

AP Regensburger, LM Fonteyne, J Jüngert… - Nature medicine, 2019 - nature.com
Biomarkers for monitoring of disease progression and response to therapy are lacking for
muscle diseases such as Duchenne muscular dystrophy. Noninvasive in vivo molecular …

3D microvascularized tissue models by laser‐based cavitation molding of collagen

A Enrico, D Voulgaris, R Östmans… - Advanced …, 2022 - Wiley Online Library
Abstract 3D tissue models recapitulating human physiology are important for fundamental
biomedical research, and they hold promise to become a new tool in drug development. An …

Hyperspectral imaging of head and neck squamous cell carcinoma for cancer margin detection in surgical specimens from 102 patients using deep learning

M Halicek, JD Dormer, JV Little, AY Chen, L Myers… - Cancers, 2019 - mdpi.com
Surgical resection of head and neck (H and N) squamous cell carcinoma (SCC) may yield
inadequate surgical cancer margins in 10 to 20% of cases. This study investigates the …

[HTML][HTML] Cardiovascular optoacoustics: From mice to men–A review

A Karlas, NA Fasoula, K Paul-Yuan, J Reber… - Photoacoustics, 2019 - Elsevier
Imaging has become an indispensable tool in the research and clinical management of
cardiovascular disease (CVD). An array of imaging technologies is considered for CVD …

Photoacoustic imaging on its way toward clinical utility: a tutorial review focusing on practical application in medicine

JJM Riksen, AV Nikolaev… - Journal of Biomedical …, 2023 - spiedigitallibrary.org
Significance Photoacoustic imaging (PAI) enables the visualization of optical contrast with
ultrasonic imaging. It is a field of intense research, with great promise for clinical application …

Photoacoustic-guided surgery from head to toe

A Wiacek, MA Lediju Bell - Biomedical Optics Express, 2021 - opg.optica.org
Photoacoustic imaging–the combination of optics and acoustics to visualize differences in
optical absorption–has recently demonstrated strong viability as a promising method to …

Optoacoustic imaging in inflammation

AP Regensburger, E Brown, G Krönke, MJ Waldner… - Biomedicines, 2021 - mdpi.com
Optoacoustic or photoacoustic imaging (OAI/PAI) is a technology which enables non-
invasive visualization of laser-illuminated tissue by the detection of acoustic signals. The …

Ultrasound-modulated optical glucose sensing using a 1645 nm laser

EY Park, J Baik, H Kim, SM Park, C Kim - Scientific Reports, 2020 - nature.com
Regular and frequent blood glucose monitoring is vital in managing diabetes treatment
plans and preventing severe complications. Because current invasive techniques impede …