Application of multimodal and molecular imaging techniques in the detection of choroidal melanomas

X Li, L Wang, L Zhang, F Tang, X Wei - Frontiers in oncology, 2021 - frontiersin.org
Choroidal melanomas are the most common ocular malignant tumors worldwide. The onset
of such tumors is insidious, such that affected patients often have no pain or obvious …

Need for a dedicated ophthalmic malignancy clinico-biological biobank: the Nice Ocular MAlignancy (NOMA) Biobank

A Martel, L Gastaud, C Bonnetaud, S Nahon-Esteve… - Cancers, 2023 - mdpi.com
Simple Summary Ophthalmic malignancies refer to rare, highly diversified, aggressive
neoplasms. Unlike other types of solid tumors, tissue biopsy is not recommended for …

Targeted next-generation sequencing of 117 routine clinical samples provides further insights into the molecular landscape of uveal melanoma

S Thornton, SE Coupland, L Olohan, JS Sibbring… - Cancers, 2020 - mdpi.com
Uveal melanoma (UM) has well-characterised somatic copy number alterations (SCNA) in
chromosomes 1, 3, 6 and 8, in addition to mutations in GNAQ, GNA11, CYSLTR2, PLCB4 …

Nanoengineered biomimetic Cu-based nanoparticles for multifunational and efficient tumor treatment

Z Chen, Q Wu, W Guo, M Niu, L Tan, N Wen, L Zhao… - Biomaterials, 2021 - Elsevier
The microwave dynamic therapy (MDT) mediated by cytotoxic reactive oxygen species
(ROS) is a promising anticancer therapeutic method. However, the therapeutic efficiency of …

Quantitative diffusion-weighted MR imaging: is there a prognostic role in noninvasively predicting the histopathologic type of uveal melanomas?

PV Foti, C Inì, G Broggi, R Farina, S Palmucci… - Cancers, 2023 - mdpi.com
Simple Summary Histologic type is an important prognostic determinant in the clinical
workup of uveal melanoma (UM), with different histologic types being related to different …

Small high-risk uveal melanomas have a lower mortality rate

RN Hussain, SE Coupland, H Kalirai, AFG Taktak… - Cancers, 2021 - mdpi.com
Simple Summary The current paradigm concerning metastatic spread in uveal melanoma is
that the critical point for dissemination occurs prior to presentation and that treatment of the …

[HTML][HTML] Cost-utility analysis of a decade of liver screening for metastases using the Liverpool Uveal Melanoma Prognosticator Online (LUMPO)

A Eleuteri, AC Rola, H Kalirai, R Hussain… - Computers in Biology …, 2021 - Elsevier
This paper outlines a method for cost-utility analysis of liver screening for metastases in
patients with posterior uveal melanoma (UM). A semiparametric model of the cumulative …

Managing vitreoretinal complications in uveal melanoma: Surgical treatment and practical considerations

R Anguita, HD Chou, VR Raval, V Bajpai… - Seminars in …, 2024 - Taylor & Francis
Background In the past few decades, the primary management for uveal melanoma has
evolved from enucleation to eye-preserving treatments. However, despite achieving a high …

Macular hole and vitreous hemorrhage subsequent to stereotactic hypofractionated radiotherapy for choroidal melanoma: A case report and review of the literature

X Zhou, H Ishikawa, F Gomi - Frontiers in Oncology, 2022 - frontiersin.org
Choroidal melanoma is the leading primary intraocular tumor with potentially fatal outcomes
in adults. The coexistence of choroidal melanoma and a macular hole is extremely rare, and …

BRCA-associated protein1 (BAP1) immunohistochemical stain reliability in postbrachytherapy uveal melanoma enucleation specimens

M Eiger-Moscovich, CL Shields… - Indian Journal of …, 2024 - journals.lww.com
Purpose: The BRCA-associated protein1 (BAP1) immunohistochemical (IHC) stain has
emerged as a powerful and inexpensive prognostic tool in uveal melanoma (UM) …