Recent advances in lipid-based long-acting injectable depot formulations
Long-acting injectable (LAIs) delivery systems sustain the drug therapeutic action in the
body, resulting in reduced dosage regimen, toxicity, and improved patient compliance. Lipid …
body, resulting in reduced dosage regimen, toxicity, and improved patient compliance. Lipid …
Recent Research Advances in Nano-Based Drug Delivery Systems for Local Anesthetics
H Ma, Z Pan, B Lai, C Zan, H Liu - Drug Design, Development and …, 2023 - Taylor & Francis
From a clinical perspective, local anesthetics have rather widespread application in regional
blockade for surgery, postoperative analgesia, acute/chronic pain control, and even cancer …
blockade for surgery, postoperative analgesia, acute/chronic pain control, and even cancer …
In vivo drug delivery applications of nanogels: a review
In recent years, nanogels have emerged as promising drug delivery vehicles; their ability in
holding active molecules, macromolecules and drugs, together with the capability to …
holding active molecules, macromolecules and drugs, together with the capability to …
A pre-formulation study of tetracaine loaded in optimized nanostructured lipid carriers
SR Castro, LNM Ribeiro, MC Breitkreitz… - Scientific reports, 2021 - nature.com
Tetracaine (TTC) is a local anesthetic broadly used for topical and spinal blockade, despite
its systemic toxicity. Encapsulation in nanostructured lipid carriers (NLC) may prolong TTC …
its systemic toxicity. Encapsulation in nanostructured lipid carriers (NLC) may prolong TTC …
Docetaxel and lidocaine co-loaded (NLC-in-hydrogel) hybrid system designed for the treatment of melanoma
Melanoma is the most aggressive skin carcinoma and nanotechnology can bring new
options for its pharmacological treatment. Nanostructured lipid carriers (NLC) are ideal drug …
options for its pharmacological treatment. Nanostructured lipid carriers (NLC) are ideal drug …
Nanogel-Based transdermal drug delivery system: A therapeutic strategy with under discussed potential
The application of nanoparticles in medication delivery has revolutionized the field of
therapeutic biology. To improve medical efficacy, currently, drug nanocarriers are employed …
therapeutic biology. To improve medical efficacy, currently, drug nanocarriers are employed …
Nanocarriers From Natural Lipids With In Vitro Activity Against Campylobacter jejuni
Campylobacter jejuni (CJ) is the most prevalent zoonotic pathogen of chicken meat and
related products, which may lead to gastroenteritis and autoimmune diseases in humans …
related products, which may lead to gastroenteritis and autoimmune diseases in humans …
Lipid nanoparticles loaded with butamben and designed to improve anesthesia at inflamed tissues
GHR da Silva, JBP Lemes, G Geronimo… - Biomaterials …, 2021 - pubs.rsc.org
The most frequently used local anesthetics (LA) for local infiltration have an ionizable amine
in the range of pH 7.6–8.9. Effective anesthesia of inflamed tissues is a great challenge …
in the range of pH 7.6–8.9. Effective anesthesia of inflamed tissues is a great challenge …
Ingenious nanoscale medication delivery system: Nanogel
Nanogels are a promising drug delivery system as they can hold drugs and macromolecules
and can also respond to external stimuli, which makes them effective tools for various …
and can also respond to external stimuli, which makes them effective tools for various …
Antinociceptive effects of bupivacaine and its sulfobutylether-β-cyclodextrin inclusion complex in orofacial pain
JS de Freitas Domingues, SMD Dos Santos… - Naunyn-Schmiedeberg's …, 2022 - Springer
Bupivacaine hydrochloride (BVC) represents an option to produce long-lasting analgesia,
and complexation in cyclodextrins has shown improvements in biopharmaceutical …
and complexation in cyclodextrins has shown improvements in biopharmaceutical …