Recent advances in lipid-based long-acting injectable depot formulations

R Sharma, S Yadav, V Yadav, J Akhtar, O Katari… - Advanced drug delivery …, 2023 - Elsevier
Long-acting injectable (LAIs) delivery systems sustain the drug therapeutic action in the
body, resulting in reduced dosage regimen, toxicity, and improved patient compliance. Lipid …

Recent Research Advances in Nano-Based Drug Delivery Systems for Local Anesthetics

H Ma, Z Pan, B Lai, C Zan, H Liu - Drug Design, Development and …, 2023 - Taylor & Francis
From a clinical perspective, local anesthetics have rather widespread application in regional
blockade for surgery, postoperative analgesia, acute/chronic pain control, and even cancer …

In vivo drug delivery applications of nanogels: a review

F Pinelli, ÓF Ortolà, P Makvandi, G Perale… - Nanomedicine, 2020 - Taylor & Francis
In recent years, nanogels have emerged as promising drug delivery vehicles; their ability in
holding active molecules, macromolecules and drugs, together with the capability to …

A pre-formulation study of tetracaine loaded in optimized nanostructured lipid carriers

SR Castro, LNM Ribeiro, MC Breitkreitz… - Scientific reports, 2021 - nature.com
Tetracaine (TTC) is a local anesthetic broadly used for topical and spinal blockade, despite
its systemic toxicity. Encapsulation in nanostructured lipid carriers (NLC) may prolong TTC …

Docetaxel and lidocaine co-loaded (NLC-in-hydrogel) hybrid system designed for the treatment of melanoma

LD de Moura, LNM Ribeiro, FV de Carvalho… - Pharmaceutics, 2021 - mdpi.com
Melanoma is the most aggressive skin carcinoma and nanotechnology can bring new
options for its pharmacological treatment. Nanostructured lipid carriers (NLC) are ideal drug …

Nanogel-Based transdermal drug delivery system: A therapeutic strategy with under discussed potential

L Tariq, A Arafah, S Ali, S Beigh, MA Dar… - Current Topics in …, 2023 - ingentaconnect.com
The application of nanoparticles in medication delivery has revolutionized the field of
therapeutic biology. To improve medical efficacy, currently, drug nanocarriers are employed …

Nanocarriers From Natural Lipids With In Vitro Activity Against Campylobacter jejuni

LNM Ribeiro, E De Paula, DA Rossi… - Frontiers in cellular …, 2021 - frontiersin.org
Campylobacter jejuni (CJ) is the most prevalent zoonotic pathogen of chicken meat and
related products, which may lead to gastroenteritis and autoimmune diseases in humans …

Lipid nanoparticles loaded with butamben and designed to improve anesthesia at inflamed tissues

GHR da Silva, JBP Lemes, G Geronimo… - Biomaterials …, 2021 - pubs.rsc.org
The most frequently used local anesthetics (LA) for local infiltration have an ionizable amine
in the range of pH 7.6–8.9. Effective anesthesia of inflamed tissues is a great challenge …

Ingenious nanoscale medication delivery system: Nanogel

A Garg, K Shah, C singh Chauhan… - Journal of Drug Delivery …, 2023 - Elsevier
Nanogels are a promising drug delivery system as they can hold drugs and macromolecules
and can also respond to external stimuli, which makes them effective tools for various …

Antinociceptive effects of bupivacaine and its sulfobutylether-β-cyclodextrin inclusion complex in orofacial pain

JS de Freitas Domingues, SMD Dos Santos… - Naunyn-Schmiedeberg's …, 2022 - Springer
Bupivacaine hydrochloride (BVC) represents an option to produce long-lasting analgesia,
and complexation in cyclodextrins has shown improvements in biopharmaceutical …