Repetitive elements in the human genome, once considered 'junk DNA', are now known to
adopt more than a dozen alternative (that is, non-B) DNA structures, such as self-annealed …

In addition to the canonical double helix, DNA can fold into various other inter-and
intramolecular secondary structures. Although many such structures were long thought to be …

Double-strand DNA breaks are common events in eukaryotic cells, and there are two major
pathways for repairing them: homologous recombination (HR) and nonhomologous DNA …

Repetitive DNA motifs are abundant in the genomes of various species and have the
capacity to adopt non-canonical (ie, non-B) DNA structures. Several non-B DNA structures …

Muntjac deer have experienced drastic karyotype changes during their speciation, making it
an ideal model for studying mechanisms and functional consequences of mammalian …

DNA becomes single stranded (ssDNA) during replication, transcription, and repair.
Transiently formed ssDNA segments can adopt alternative conformations, including …

Recent discoveries have revealed that simple repeating DNA sequences, which are known
to adopt non-B DNA conformations (such as triplexes, cruciforms, slipped structures, left …

DNA inverted repeats (IRs) are hotspots of genomic instability in both prokaryotes and
eukaryotes. This feature is commonly attributed to their ability to fold into hairpin-or cruciform …

Repetitive genomic sequences can adopt a number of alternative DNA structures that differ
from the canonical B-form duplex (ie non-B DNA). These non-B DNA-forming sequences …

Gross chromosomal rearrangements (including translocations, deletions, insertions and
duplications) are a hallmark of cancer genomes and often create oncogenic fusion genes …