[HTML][HTML] Macrophage M1 polarization mediated via the IL-6/STAT3 pathway contributes to apical periodontitis induced by Porphyromonas gingivalis
X Chen, J Dou, Z Fu, Y Qiu, L Zou, D Huang… - Journal of Applied Oral …, 2022 - SciELO Brasil
Objective: To investigate the involvement of IL-6/STAT3 signaling pathway activation in
macrophage polarization and bone destruction related to apical periodontitis (AP) stimulated …
macrophage polarization and bone destruction related to apical periodontitis (AP) stimulated …
The Effects of Porphyromonas gingivalis on Inflammatory and Immune Responses and Osteogenesis of Mesenchymal Stem Cells
J Yu, S Chen, S Lei, F Li, Y Wang, X Shu… - Stem Cells and …, 2021 - liebertpub.com
Mesenchymal stem cells (MSCs) are increasingly used in tissue regeneration, not only
because of their multilineage differentiation ability, but also because of their …
because of their multilineage differentiation ability, but also because of their …
CKIP-1 mediates P. gingivalis-suppressed osteogenic/cementogenic differentiation of periodontal ligament cells partially via p38 signaling pathway
X Huang, J Xiao, H Wang, Y Peng, H Liu… - Journal of Oral …, 2023 - Taylor & Francis
Objectives Casein kinase 2 interacting protein-1 (CKIP-1) is a versatile player involved in
various biological processes. However, whether CKIP-1 mediates the osteogenic …
various biological processes. However, whether CKIP-1 mediates the osteogenic …
Microbial–stem cell interactions in periodontal disease
JM Iliopoulos, P Layrolle… - Journal of Medical …, 2022 - microbiologyresearch.org
Periodontitis is initiated by hyper-inflammatory responses in the periodontal tissues that
generate dysbiotic ecological changes within the microbial communities. As a result …
generate dysbiotic ecological changes within the microbial communities. As a result …
Human β-defensin 3-combined gold nanoparticles for enhancement of osteogenic differentiation of human periodontal ligament cells in inflammatory …
J Zhou, Y Zhang, L Li, H Fu, W Yang… - International Journal of …, 2018 - Taylor & Francis
Objective It is a great challenge to absorb and conduct biophysicochemical interactions at
the nano-bio interface. Peptides are emerging as versatile materials whose function can be …
the nano-bio interface. Peptides are emerging as versatile materials whose function can be …
Periodontal ligament‐derived mesenchymal stem cells modulate neutrophil responses via paracrine mechanisms
MYO Misawa, KG Silverio Ruiz… - Journal of …, 2019 - Wiley Online Library
Background Mesenchymal stem cells differentiate into distinct mesenchymal cell lineages
and regulate the immune response. The aim of this study was to determine whether …
and regulate the immune response. The aim of this study was to determine whether …
Pathogenesis‐Guided Engineering: pH‐Responsive Imprinted Polymer Co‐Delivering Folate for Inflammation‐Resolving as Immunotherapy in Implant‐Related …
Folate (FT) is a suitable targeting ligand for folate receptors (FOLR) overexpressed on
inflamed cells. Thus, FT‐loaded polymers can be used as FOLRs‐targeted immunotherapy …
inflamed cells. Thus, FT‐loaded polymers can be used as FOLRs‐targeted immunotherapy …
Immune response characterization of primary gingival fibroblasts from Grade C periodontitis patients
CS Stolf, CM Sacramento… - Journal of …, 2023 - Wiley Online Library
Abstract Background Grade C, Stage 3–4 Periodontitis (Perio4C) is a rapidly destructive
disease caused by an unequilibrated immune response that starts after the primary contact …
disease caused by an unequilibrated immune response that starts after the primary contact …
The impact of Thiopeptide antibiotics on inflammatory responses in periodontal tissues through the regulation of the MAPK pathway
J Lyu, S Shen, Y Hao, M Zhou, J Tao - International Immunopharmacology, 2024 - Elsevier
Periodontitis is a bacteria-induced inflammatory disease that damages the tissues
supporting the teeth, gums, periodontal ligaments, and alveolar bone. Conventional …
supporting the teeth, gums, periodontal ligaments, and alveolar bone. Conventional …
IL10 promoter rs6667202 polymorphism is functional in health but not in grade c periodontitis patients: A pilot study
Background and objective Previous studies have demonstrated an association between the
IL10 promoter rs6667202 (C> A) single‐nucleotide polymorphism (SNP) and grade C, stage …
IL10 promoter rs6667202 (C> A) single‐nucleotide polymorphism (SNP) and grade C, stage …