Protein nanoparticles: uniting the power of proteins with engineering design approaches

N Habibi, A Mauser, Y Ko, J Lahann - Advanced Science, 2022 - Wiley Online Library
Protein nanoparticles, PNPs, have played a long‐standing role in food and industrial
applications. More recently, their potential in nanomedicine has been more widely pursued …

Rolling cell adhesion

RP McEver, C Zhu - Annual review of cell and developmental …, 2010 - annualreviews.org
Rolling adhesion on vascular surfaces is the first step in recruiting circulating leukocytes,
hematopoietic progenitors, or platelets to specific organs or to sites of infection or injury …

The minimal cadherin-catenin complex binds to actin filaments under force

CD Buckley, J Tan, KL Anderson, D Hanein… - Science, 2014 - science.org
INTRODUCTION Cadherins are an ancient class of transmembrane proteins that are
essential for the formation of multicellular tissues in metazoans. Cadherins link intercellular …

The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness

J Huang, VI Zarnitsyna, B Liu, LJ Edwards, N Jiang… - Nature, 2010 - nature.com
The T-cell receptor (TCR) interacts with peptide-major histocompatibility complexes (pMHC)
to discriminate pathogens from self-antigens and trigger adaptive immune responses. Direct …

Selectins—the two Dr. Jekyll and Mr. Hyde faces of adhesion molecules—a review

I Tvaroška, C Selvaraj, J Koča - Molecules, 2020 - mdpi.com
Selectins belong to a group of adhesion molecules that fulfill an essential role in immune
and inflammatory responses and tissue healing. Selectins are glycoproteins that decode the …

Biomechanics of leukocyte rolling

P Sundd, MK Pospieszalska, LSL Cheung… - …, 2011 - content.iospress.com
Leukocyte rolling on endothelial cells and other P-selectin substrates is mediated by P-
selectin binding to P-selectin glycoprotein ligand-1 expressed on the tips of leukocyte …

T-cell mechanobiology: force sensation, potentiation, and translation

DL Harrison, Y Fang, J Huang - Frontiers in physics, 2019 - frontiersin.org
AT cell is a sensitive self-referential mechanical sensor. Mechanical forces influence the
recognition, activation, differentiation, and function throughout the lifetime of a T cell. T cells …

Mechanomics: an emerging field between biology and biomechanics

J Wang, D Lü, D Mao, M Long - Protein & cell, 2014 - academic.oup.com
Cells sense various in vivo mechanical stimuli, which initiate downstream signaling to
mechanical forces. While a body of evidences is presented on the impact of limited …

Dual Affinity Nanoparticles for the Transport of Therapeutics from Carrier Cells to Target Cells under Physiological Flow Conditions

M Lopez-Cavestany, OA Wright, AM Cassidy… - ACS …, 2023 - ACS Publications
In this study, a novel two-stage nanoparticle delivery platform was developed based on the
dual functionalization of a liposome with moieties that have fundamentally different strengths …

[图书][B] Animal lectins: form, function and clinical applications

GS Gupta - 2012 - books.google.com
Animal Lectins: Form, Function and Clinical Applications presents up-to-date knowledge of
animal lectins. Detailed descriptions on biological activities, tissue and/or subcellular …