Cannabidiol adverse effects and toxicity

MA Huestis, R Solimini, S Pichini… - Current …, 2019 - ingentaconnect.com
Background: Currently, there is a great interest in the potential medical use of cannabidiol
(CBD), a non-intoxicating cannabinoid. Productive pharmacological research on CBD …

Cannabidiol: a potential new alternative for the treatment of anxiety, depression, and psychotic disorders

MS García-Gutiérrez, F Navarrete, A Gasparyan… - Biomolecules, 2020 - mdpi.com
The potential therapeutic use of some Cannabis sativa plant compounds has been attracting
great interest, especially for managing neuropsychiatric disorders due to the relative lack of …

Reasons for cannabidiol use: a cross-sectional study of CBD users, focusing on self-perceived stress, anxiety, and sleep problems

J Moltke, C Hindocha - Journal of cannabis research, 2021 - Springer
Background Public and medical interest in cannabidiol (CBD) has been rising, and CBD is
now available from various sources. Research into the effects of low-dose CBD on outcomes …

Cannabidiol: State of the art and new challenges for therapeutic applications

S Pisanti, AM Malfitano, E Ciaglia, A Lamberti… - Pharmacology & …, 2017 - Elsevier
Over the past years, several lines of evidence support a therapeutic potential of Cannabis
derivatives and in particular phytocannabinoids. Δ 9-THC and cannabidiol (CBD) are the …

Medicinal properties of cannabinoids, terpenes, and flavonoids in cannabis, and benefits in migraine, headache, and pain: an update on current evidence and …

EP Baron - Headache: The Journal of Head and Face Pain, 2018 - Wiley Online Library
Background Comprehensive literature reviews of historical perspectives and evidence
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …

Psychiatric symptoms caused by cannabis constituents: a systematic review and meta-analysis

G Hindley, K Beck, F Borgan, CE Ginestet… - The Lancet …, 2020 - thelancet.com
Background Approximately 188 million people use cannabis yearly worldwide, and it has
recently been legalised in 11 US states, Canada, and Uruguay for recreational use. The …

Evolution and Classification of Cannabis sativa (Marijuana, Hemp) in Relation to Human Utilization

E Small - The botanical review, 2015 - Springer
Cannabis sativa has been employed for thousands of years, primarily as a source of a stem
fiber (both the plant and the fiber termed “hemp”) and a resinous intoxicant (the plant and its …

Cannabidiol (CBD) use in psychiatric disorders: A systematic review

S Bonaccorso, A Ricciardi, C Zangani, S Chiappini… - Neurotoxicology, 2019 - Elsevier
Abstract Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) are the most represented
phytocannabinoids in Cannabis sativa plants. However, CBD may present with a different …

Taming THC: potential cannabis synergy and phytocannabinoid‐terpenoid entourage effects

EB Russo - British journal of pharmacology, 2011 - Wiley Online Library
Tetrahydrocannabinol (THC) has been the primary focus of cannabis research since 1964,
when Raphael Mechoulam isolated and synthesized it. More recently, the synergistic …

The essential medicinal chemistry of cannabidiol (CBD)

KM Nelson, J Bisson, G Singh, JG Graham… - Journal of medicinal …, 2020 - ACS Publications
This Perspective of the published essential medicinal chemistry of cannabidiol (CBD)
provides evidence that the popularization of CBD-fortified or CBD-labeled health products …