Chronic wounds represent a major global health problem, causing staggering economic and
social burdens. The pursuit of effective wound healing strategies demands a …

With the long persistence of complex, chronic diseases in society, there is increasing
motivation to develop cells as living medicine to treat diseases ranging from cancer to …

Under diabetic circumstances, keratinocytes are constantly exposed to hyperglycaemic
micromilieu, leading to disrupted differentiation and increased chronic wound susceptibility …

A long-term inflammatory phase of diabetic wounds is the primary cause to prevent their
effective healing. Bacterial infection, excess reactive oxygen species (ROS), especially …

The number of patients with non-healing wounds continuously increase, which has become
a prominent societal issue that imposes a heavy burden on both patients and the entire …

Wound healing is a crucial but complex process that represents an onerous burden on both
individuals and the healthcare system in the alarming growth of chronic diseases. Infection …

Clinical studies have continually referred to the involvement of drug carrier having dramatic
negative influences on the biocompatibility, biodegradability, and loading efficacy of …

The extracellular matrix (ECM) orchestrates cell behavior and tissue regeneration by
modulating biochemical and mechanical signals. Manipulating cell–material interactions is …

Wound healing involves distinct phases, including hemostasis, inflammation, proliferation,
and remodeling, which is a complex and dynamic process. Conventional preparations often …

Diabetic wound infection has always been a huge threat to human's healthcare, and most of
the existing therapies have reduced efficacy, drug resistance and toxic side effects …