Technological advances enabling massively parallel measurement of biological features—
such as microarrays, high-throughput sequencing and mass spectrometry—have ushered in …

Comparing genomic and biological characteristics across multiple species is essential to
using model systems to investigate the molecular and cellular mechanisms underlying …

Advancements in comparative genomics research have led to a growing interest in studying
species evolution and genetic diversity. To facilitate this research, OrthoVenn3 has been …

The KEGG database and analysis tools (https://www. kegg. jp) have been developed mostly
for understanding genes and genomes of cellular organisms. The KO (KEGG Orthology) …

The surge in genome data, with ongoing efforts aiming to sequence 1.5 M eukaryotes in a
decade, could revolutionize genomics, revealing the origins, evolution and genetic …

MicroRNAs (miRNAs) are post-transcriptional regulators that finetune gene expression via
translational repression or degradation of their target mRNAs. Despite their functional …

Accurate inference of orthologous genes constitutes a prerequisite for comparative and
evolutionary genomics. SonicParanoid is one of the fastest tools for orthology inference; …

Prediction of orthologs is an important bioinformatics pursuit that is frequently used for
inferring protein function and evolutionary analyses. The InParanoid database is a well …

Crop pangenomes made from individual cultivar assemblies promise easy access to
conserved genes, but genome content variability and inconsistent identifiers hamper their …

Understanding the origin of eukaryotic cells is one of the most difficult problems in all of
biology. A key challenge relevant to the question of eukaryogenesis is reconstructing the …