Colonic potassium handling
Homeostatic control of plasma K+ is a necessary physiological function. The daily dietary K+
intake of~ 100 mmol is excreted predominantly by the distal tubules of the kidney. About …
intake of~ 100 mmol is excreted predominantly by the distal tubules of the kidney. About …
H+-K+-ATPases: regulation and role in pathophysiological states
RB Silver, M Soleimani - American Journal of Physiology …, 1999 - journals.physiology.org
Molecular cloning experiments have identified the existence of two H+-K+-ATPases (HKAs),
colonic and gastric. Recent functional and molecular studies indicate the presence of both …
colonic and gastric. Recent functional and molecular studies indicate the presence of both …
Increased sensitivity to K+ deprivation in colonic H, K-ATPase-deficient mice.
P Meneton, PJ Schultheis, J Greeb… - The Journal of …, 1998 - Am Soc Clin Investig
Previous studies using isolated tissues suggest that the colonic H, K-ATPase (cHKA),
expressed in the colon and kidney, plays an important role in K+ conservation. To test the …
expressed in the colon and kidney, plays an important role in K+ conservation. To test the …
Nonionic diffusion of short-chain fatty acids across rat colon
AN Charney, L Micic, RW Egnor - American Journal of …, 1998 - journals.physiology.org
Short-chain fatty acid (SCFA) transport across the colon may occur by nonionic diffusion
and/or via apical membrane SCFA−/HCO 3− exchange. To examine the relative importance …
and/or via apical membrane SCFA−/HCO 3− exchange. To examine the relative importance …
[HTML][HTML] Colonic potassium absorption and secretion in health and disease
VM Rajendran, GI Sandle - Comprehensive Physiology, 2018 - ncbi.nlm.nih.gov
The colon has large capacities for K+ absorption and K+ secretion, but its role in maintaining
K+ homeostasis is often overlooked. For many years, passive diffusion and/or solvent drag …
K+ homeostasis is often overlooked. For many years, passive diffusion and/or solvent drag …
[HTML][HTML] The Rat Distal Colon P-ATPase α Subunit Encodes a Ouabain-sensitive H+, K+-ATPase (∗)
M Cougnon, G Planelles, MS Crowson, GE Shull… - Journal of Biological …, 1996 - ASBMB
The functional properties and the pharmacological profile of the recently cloned cDNA
colonic P-ATPase α subunit (Crowson, MS, and Shull, GE (1992) J. Biol. Chem. 267, 13740 …
colonic P-ATPase α subunit (Crowson, MS, and Shull, GE (1992) J. Biol. Chem. 267, 13740 …
[HTML][HTML] Pancreatic bicarbonate secretion involves two proton pumps
Pancreas secretes fluid rich in digestive enzymes and bicarbonate. The alkaline secretion is
important in buffering of acid chyme entering duodenum and for activation of enzymes. This …
important in buffering of acid chyme entering duodenum and for activation of enzymes. This …
HK-ATPase type 2: relevance for renal physiology and beyond
G Crambert - American Journal of Physiology-Renal …, 2014 - journals.physiology.org
HK-ATPase type 2 (HKA2), also known as the “nongastric” or “colonic” HK-ATPase, is
broadly expressed, and its presence in the kidney has puzzled experts in the field of renal …
broadly expressed, and its presence in the kidney has puzzled experts in the field of renal …
Regulation of colonic HK-ATPase in large intestine and kidney by dietary Na depletion and dietary K depletion
P Sangan, VM Rajendran, AS Mann… - … of Physiology-Cell …, 1997 - journals.physiology.org
Active K absorption in the rat distal colon is energized by an apical membrane HK-ATPase,
whereas K absorption in the distal collecting duct is generally believed to be modulated by a …
whereas K absorption in the distal collecting duct is generally believed to be modulated by a …
The nongastric H+-K+-ATPases: molecular and functional properties
F Jaisser, AT Beggah - American Journal of Physiology …, 1999 - journals.physiology.org
The Na-K/HK-ATPase gene family is divided in three subgroups including the Na-K-
ATPases, mainly involved in whole body and cellular ion homeostasis, the gastric HK …
ATPases, mainly involved in whole body and cellular ion homeostasis, the gastric HK …