Concussion: pathophysiology and clinical translation

C Giza, T Greco, ML Prins - Handbook of clinical neurology, 2018 - Elsevier
The majority of the 3.8 million estimated annual traumatic brain injuries (TBI) in the United
States are mild TBIs, or concussions, and they occur primarily in adolescents and young …

Mechanisms underlying vulnerabilities after repeat mild traumatic brain injuries

T Greco, L Ferguson, C Giza, ML Prins - Experimental neurology, 2019 - Elsevier
Traumatic brain injury (TBI) has drawn national attention for its high incidence and
mechanistic complexity. The majority of TBI cases are “mild” in nature including concussions …

Systematic image‐driven analysis of the spatial Drosophila embryonic expression landscape

E Frise, AS Hammonds, SE Celniker - Molecular systems biology, 2010 - embopress.org
Discovery of temporal and spatial patterns of gene expression is essential for understanding
the regulatory networks and development in multicellular organisms. We analyzed the …

Enhanced XAO: the ontology of Xenopus anatomy and development underpins more accurate annotation of gene expression and queries on Xenbase

E Segerdell, VG Ponferrada, C James-Zorn… - Journal of biomedical …, 2013 - Springer
Abstract Background The African clawed frogs Xenopus laevis and Xenopus tropicalis are
prominent animal model organisms. Xenopus research contributes to the understanding of …

Systems biology approaches to heart development and congenital heart disease

SR Sperling - Cardiovascular research, 2011 - academic.oup.com
Even though the foundation of systems biology approaches to cardiac function was led more
than fifty years ago, there has been slow progression over the last few decades. Systems …

Eye field specification in Xenopus laevis

ME Zuber - Current topics in developmental biology, 2010 - Elsevier
Vertebrate eyes begin as a small patch of cells at the most anterior end of the early brain
called the eye field. If these cells are removed from an amphibian embryo, the eyes do not …

Toolbox in a tadpole: Xenopus for kidney research

M Getwan, SS Lienkamp - Cell and tissue research, 2017 - Springer
Xenopus is a versatile model organism increasingly used to study organogenesis and
genetic diseases. The rapid embryonic development, targeted injections, loss-and gain-of …

A Database of microRNA Expression Patterns in Xenopus laevis

A Ahmed, NJ Ward, S Moxon, S Lopez-Gomollon… - PloS one, 2015 - journals.plos.org
MicroRNAs (miRNAs) are short, non-coding RNAs around 22 nucleotides long. They inhibit
gene expression either by translational repression or by causing the degradation of the …

A large scale screen for neural stem cell markers in Xenopus retina

K Parain, N Mazurier, O Bronchain… - Developmental …, 2012 - Wiley Online Library
Neural stem cell research suffers from a lack of molecular markers to specifically assess
stem or progenitor cell properties. The organization of the Xenopus ciliary marginal zone …

PvGeneExpDB: An integrative gene expression database for in-depth understanding on the Pacific white shrimp (Litopenaeus vannamei)

X Xiong, C Xie, S Li, Y Wang, J Jiang, D Xie… - … and Physiology Part D …, 2024 - Elsevier
Abstract The Pacific white shrimp (Litopenaeus vannamei) is a high-valued economic
farming species. With the development of high-throughput sequencing technology …