Insulin action is impaired in type 2 diabetes. The functions of the hormone are an integrated
product of insulin secretion from pancreatic β-cells and insulin clearance by receptor …

Hypomagnesemia is 10-fold more common in individuals with type 2 diabetes (T2D) than in
the healthy population. Factors that are involved in this high prevalence are low Mg2+ …

The primary genetic, environmental, and metabolic factors responsible for causing insulin
resistance and pancreatic β-cell failure and the precise sequence of events leading to the …

Purpose of review Insulin resistance (IR) is recognized to play an important role in the
pathogenesis of dyslipidemia. This review summarizes the complex interplay between IR …

Plasma free fatty acids (FFA) might mediate the insulin resistance and impaired glucose
tolerance associated with central obesity. Central adipocytes are resistant to insulin …

Metabolic syndrome: definition, pathophysiology, and mechanisms. - Abstract - Europe
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Obesity is strongly associated with metabolic syndrome. Recent research suggests that
excess adipose tissue plays an important role in development of the syndrome. On the other …

Chronic inflammation is closely associated with metabolic disorders such as obesity and
type 2 diabetes, however, the underlying mechanism is unclear. Toll-like receptors (TLRs) …

Context: Visfatin was recently identified as a protein highly expressed and secreted in
adipose tissue with insulin-mimetic effect and is a candidate hormone to help explain the …

The associations between obesity, insulin resistance, and type 2 diabetes mellitus are well
documented. Free fatty acids (FFA), which are often elevated in obesity, have been …