[HTML][HTML] A comprehensive review on pharmacological, toxicity, and pharmacokinetic properties of phillygenin: Current landscape and future perspectives

C Wang, R Wu, S Zhang, L Gong, K Fu, C Yao… - Biomedicine & …, 2023 - Elsevier
Forsythiae Fructus is a traditional Chinese medicine frequently in clinics. It is extensive in the
treatment of various inflammation-related diseases and is renowned as' the holy medicine of …

Overview of first-line and second-line pharmacotherapies for osteoarthritis with special focus on intra-articular treatment

A Nowaczyk, D Szwedowski, I Dallo… - International Journal of …, 2022 - mdpi.com
Osteoarthritis (OA) can be defined as the result of pathological processes of various
etiologies leading to damage to the articular structures. Although the mechanism of …

Efficacy and mechanism of the Ermiao San series of formulas for rheumatoid arthritis based on Chinmedomics strategy

H Liu, L Kong, D Cao, X Zhan, X Gao, H Sun, G Yan… - Phytomedicine, 2024 - Elsevier
Abstract Background The Ermiao San Series of Formulas (ESSF) refers to Ermiao San (TS),
Sanmiao Wan (TW), and Simiao Wan (FW), which are widely used traditional Chinese …

Immune effects of macrophages in rheumatoid arthritis: a bibliometric analysis from 2000 to 2021

YL Xu, Z Zhang, J He, Z Chen - Frontiers in Immunology, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease characterized by
macrophage activation. The current characteristics, hotspots, and research frontiers of …

[HTML][HTML] Development of pH-sensitive dextran-based methotrexate nanodrug for rheumatoid arthritis therapy through inhibition of JAK-STAT pathways

X Wang, W Cao, C Sun, Y Wang, M Wang… - International Journal of …, 2022 - Elsevier
Rheumatoid arthritis (RA) is a chronic and symmetrical autoimmune disease that primarily
characterized with articular synovial hyperplasia, joint swelling, cartilage and bone …

Deep eutectic solvents—Hydrogels for the topical management of rheumatoid arthritis

M Li, H Cui, Y Cao, Y Lin, Y Yang, M Gao… - Journal of Controlled …, 2023 - Elsevier
Deep eutectic solvents (DES) have demonstrated their ability to facilitate skin penetrability of
rigid nanoparticles (NPs). Here, we reported a feasible and simple transdermal delivery …

Magnoflorine ameliorates collagen-induced arthritis by suppressing the inflammation response via the NF-κB/MAPK signaling pathways

L Wang, P Li, Y Zhou, R Gu, G Lu… - Journal of Inflammation …, 2023 - Taylor & Francis
Objective Magnoflorine (Mag) has been reported to have anxiolytics, anti-cancer, and anti-
inflammatory properties. In this study, we aim to investigate the effects of Mag on the …

Determination of Therapeutic and Safety Effects of Zygophyllum coccineum Extract in Induced Inflammation in Rats

M Yosri, MM Elaasser, MM Abdel-Aziz… - BioMed Research …, 2022 - Wiley Online Library
Background. Z. coccineum is a facultative plant with many medicinal applications. This study
examined the anti‐inflammatory activity of Zygophyllum coccineum (Z. coccineum) in an …

Shikonin suppresses rheumatoid arthritis by inducing apoptosis and autophagy via modulation of the AMPK/mTOR/ULK-1 signaling pathway

X Wang, C Shen, T Wang, Y Huang, Y Jin, M Zhou… - Phytomedicine, 2024 - Elsevier
Background The overproliferation of fibroblast-like synoviocytes (FLS) contributes to
synovial hyperplasia, a pivotal pathological feature of rheumatoid arthritis (RA). Shikonin …

Sulfasalazine promotes ferroptosis through AKT-ERK1/2 and P53-SLC7A11 in rheumatoid arthritis

C Zhao, Y Yu, G Yin, C Xu, J Wang, L Wang… - …, 2024 - Springer
Objective Ferroptosis has been reported to play a role in rheumatoid arthritis (RA).
Sulfasalazine, a common clinical treatment for ankylosing spondylitis, also exerts …