With an increasing interest in cocrystals due to various advantages, demand for large-scale
cocrystallization techniques is rising. Solution cocrystallization is a solvent-based approach …

The design and synthesis of pharmaceutical cocrystals have received great interest in the
recent years. Cocrystallization of drug substances offers a tremendous opportunity for the …

Purpose To improve the solubility of carvedilol by preparing cocrystals utilizing solvent-free,
continuous technology hot melt extrusion. Methods Cocrystals of carvedilol and …

Co-crystallization is a new approach of enhancement of solubility, stability, bioavailability
and other physicochemical properties. It offers a better optimization of physical and …

Oromucosal delivery of olanzapine (OLZ) is an optimal strategy to overcome low oral
bioavailability as well as improve medication adherence. However, its poor aqueous …

Abstract Carbamazepine-saccharin (CBZ-SAC) co-crystal is one of the most studied co-
crystals to date. It is proven to be polymorphic, consisting of Form I (plate-like shape) and …

In recent years, the design of pharmaceutical cocrystals has garnered significant attention.
The process of cocrystallization offers a remarkable opportunity to develop drug products …

Lopinavir is a BCS class II antiretroviral drug with mild hygroscopic characteristics
necessitating approaches to improve dissolution and control the humidity. Cocrystals offer a …

Aim: The aim of the present study was to develop sustained release drug delivery system of
neuroleptic drug (Carbamazepine). Oral route is considered as one of the most popular, non …

Drug discovery is a critical process required to identify a therapeutic compound or active
pharmaceutical ingredient used for curing a disease. One of the setbacks for this API is its …