Nanodiscs are self-assembled discoidal fragments of lipid bilayers 8–16 nm in diameter,
stabilized in solution by two amphipathic helical scaffold proteins. As stable and highly …

Information exchange is essential for the brain, where it communicates the physiological and
pathological signals to the periphery and vice versa. Extracellular vesicles (EVs) are a …

[Frontiers in Bioscience E4, 289-299, January 1, 2012] 289 Tissue factor in blood cells and
endothelial cells Bjarne Osterud1, 2 Page 1 [Frontiers in Bioscience E4, 289-299, January 1 …

Chitosan/gelatin (CG) composite sponges containing oxidized cellulose fibers (OF)
crosslinked with tannic acid were fabricated by freeze-drying as hemostatic agents. The …

The blood coagulation balance in the organism is achieved by the interaction of the blood
platelets (PLTs) with the plasma coagulation system (PCS) and the vascular endothelial …

In this study, we characterized tissue factor (TF) expression in mouse hepatocytes (HPCs)
and evaluated its role in mouse models of HPC transplantation and acetaminophen (APAP) …

The clotting factor prothrombin exists in equilibrium between closed and open
conformations, but the physiological role of these forms remains unclear. As for other …

Molecular dynamics methodologies comprise a vital research tool for structural biology.
Molecular dynamics has benefited from technological advances in computing, such as …

Activated factor VII–anti-thrombin (FVIIa-AT) complex is a potential biomarker of pro-
thrombotic diathesis reflecting FVIIa–tissue factor (TF) interaction and has been associated …

A flexible linker (Lnk2) composed of 26 amino acids connects kringle-1 to kringle-2 in the
coagulation factor prothrombin. Recent studies point to Lnk2 as a key determinant of the …