All components of the CNS are surrounded by a diffuse extracellular matrix (ECM)
containing chondroitin sulphate proteoglycans (CSPGs), heparan sulphate proteoglycans …

Microglia shape the synaptic environment in health and disease, but synapses do not exist
in a vacuum. Instead, pre-and postsynaptic terminals are surrounded by extracellular matrix …

Perineuronal nets (PNNs) are specialized extracellular matrix structures that surround
specific neurons in the brain and spinal cord, appear during critical periods of development …

Perineuronal nets (PNNs) surround specific neurons in the brain and are involved in various
forms of plasticity and clinical conditions. However, our understanding of the PNN role in …

As chemically specialized forms of the extracellular matrix in the central nervous system,
polyanionic perineuronal nets (PNs) contain diverse constituents, including chondroitin …

Perineuronal nets (PNNs) are specialized structures of the extracellular matrix that surround
the soma and proximal dendrites of certain neurons in the central nervous system …

Stress-related psychiatric disorders including depression involve complex cellular and
molecular changes in the brain, and GABAergic signaling dysfunction is increasingly …

Schizophrenia is a grave neuropsychiatric disease which frequently onsets between the end
of adolescence and the beginning of adulthood. It is characterized by a variety of …

Overindulgence, excessive consumption, and a pattern of compulsive use of natural
rewards, such as certain foods or drugs of abuse, may result in the development of obesity …

The medial prefrontal cortex (mPFC) drives cocaine‐seeking behaviour in rodent models of
cocaine use disorder. Parvalbumin (PV)‐containing GABAergic interneurons powerfully …