Cognitive functioning is moderately to severely impaired in patients with schizophrenia. This
impairment is the prime driver of the significant disabilities in occupational, social, and …

Until recently, the dominant view was that schizophrenia patients have limited, if any,
neuropsychological impairments, and those that are observed are only secondary to the …

Context Neurocognitive impairment in schizophrenia is severe and is an important predictor
of functional outcome. The relative effect of the second-generation (atypical) antipsychotic …

Cognitive impairment is a core feature of schizophrenia and a major impediment to social
and vocational rehabilitation. A number of studies have claimed cognitive benefits from …

Context Cognitive impairment in schizophrenia is frequent, involves multiple domains, and is
enduring. Numerous recent clinical trials have suggested that second-generation …

BACKGROUND: In recent years, numerous studies have examined whether new-generation
antipsychotic agents impact cognitive impairment in patients with schizophrenia when …

Objective: Schizophrenia is treated with medications that raise serum anticholinergic activity
and are known to adversely affect cognition. The authors examined the relationship between …

Background: Truly effective treatments for schizophrenia require much more than clinical
efficacy. Symptom improvement is all that is required to demonstrate clinical efficacy …

Background: The purpose of this historical prospective study was to follow the cognitive
impairment in schizophrenia from the premorbid period until shortly after the onset of the first …

The early course of neuropsychological dysfunction in schizophrenia and the impact of
treatment on these deficits need to be better specified. A sample of 45 patients with …