Despite aging being by far the greatest risk factor for highly prevalent neurodegenerative
disorders, the molecular underpinnings of age-related brain changes are still not well …

Vascular dementia (VaD) is the second leading form of dementia after Alzheimer's disease
(AD) plaguing the elderly population. VaD is a progressive disease caused by reduced …

Background Modification of the gut microbiota has been reported to reduce the incidence of
type 1 diabetes mellitus (T1D). We hypothesized that the gut microbiota shifts might also …

Diabetes mellitus-induced metabolic disturbances underlie the action of many systems
including some higher functions of the brain such as learning and memory. Plenty of …

Diabetes often leads to a number of complications involving brain function, including
cognitive decline and depression. In addition, depression is a risk factor for developing …

The aim of the present study was to analyze the action of metformin on short-term memory,
glial cell activation and neuroinflammation caused by experimental diabetic encephalopathy …

The adult mammalian brain contains a population of neural stem cells that can give rise to
neurons, astrocytes, and oligodendrocytes and are thought to be involved in certain forms of …

Curcumin is a natural polyphenol with evidence of antioxidant, anti-inflammatory and
neuroprotective properties. Recent evidence also suggests that curcumin increases …

Background: High-fat, low-carbohydrate diets are widely used for weight reduction, but they
may also have detrimental effects via increased circulating free fatty acid concentrations …

Background: Diabetes mellitus is associated with cognitive deficits in humans and animals.
These deficits are paralleled by neurophysiological and structural changes in brain. In …