The incidence of sepsis is highest in neonates and children, yet the global burden of sepsis
in these age groups has not been assessed. We reviewed available evidence from …

Objective: The first 70 years of critical care can be considered a period of “industrial
revolution-like” advancement in terms of progressing the understanding and care of critical …

Staphylococcus aureus (S. aureus) is an asymptomatic colonizer of 30% of all human
beings. While generally benign, antibiotic resistance contributes to the success of S. aureus …

Background Hospital-associated infections (HAIs) are an important cause of morbidity and
mortality around the world. Many HAIs are caused by drug-resistant bacterial pathogens, but …

Healthcare-associated infections (HAIs) are caused by nosocomial pathogens. HAIs have
an immense impact not only on developing countries but also on highly developed parts of …

Background Improving the quality of hospital antibiotic use is a major goal of WHO's global
action plan to combat antimicrobial resistance. The WHO Essential Medicines List Access …

Health-care-associated infections (HAIs) are considered a serious public health issues that
contribute substantially to the global burden of mortality and morbidity with respect to …

Background: Hospital-acquired infections (HAI) contribute to the emotional stress and
functional disorders of the patient and in some cases, can lead to a state of disability that …

Background Sepsis is one of the main reasons for non-elective admission to pediatric
intensive care units (PICUs), but little is known about determinants influencing outcome. We …

Background Central line-associated bloodstream infections (CLABSIs) are associated with
increased mortality, prolonged hospitalisation and increased healthcare costs. Care bundles …