Molecular mechanisms of neuroplasticity: an expanding universe

NV Gulyaeva - Biochemistry (Moscow), 2017 - Springer
Biochemical processes in synapses and other neuronal compartments underlie
neuroplasticity (functional and structural alterations in the brain enabling adaptation to the …

Astrocyte regulation of synaptic signaling in psychiatric disorders

A Kruyer, PW Kalivas, MD Scofield - Neuropsychopharmacology, 2023 - nature.com
Over the last 15 years, the field of neuroscience has evolved toward recognizing the critical
role of astroglia in shaping neuronal synaptic activity and along with the pre-and …

Long-term neuroinflammation induced by influenza A virus infection and the impact on hippocampal neuron morphology and function

S Hosseini, E Wilk, K Michaelsen-Preusse… - Journal of …, 2018 - Soc Neuroscience
Acute influenza infection has been reported to be associated with neurological symptoms.
However, the long-term consequences of an infection with neurotropic and non-neurotropic …

Intranasal delivery of mesenchymal stem cell secretome repairs the brain of Alzheimer's mice

G Santamaria, E Brandi, PL Vitola, F Grandi… - Cell Death & …, 2021 - nature.com
The multiplicity of systems affected in Alzheimer's disease (AD) brains calls for multi-target
therapies. Although mesenchymal stem cells (MSC) are promising candidates, their clinical …

Microglia control glutamatergic synapses in the adult mouse hippocampus

B Basilico, L Ferrucci, P Ratano, MT Golia, A Grimaldi… - Glia, 2022 - Wiley Online Library
Microglia cells are active players in regulating synaptic development and plasticity in the
brain. However, how they influence the normal functioning of synapses is largely unknown …

Toll-like receptor 4-dependent glial cell activation mediates the impairment in memory establishment induced by β-amyloid oligomers in an acute mouse model of …

C Balducci, A Frasca, M Zotti, P La Vitola… - Brain, behavior, and …, 2017 - Elsevier
Background: Amyloid-β oligomers (AβO) are species mainly involved in the synaptic and
cognitive dysfunction in Alzheimer's disease. Although their action has been described …

[HTML][HTML] The protective effect of thymoquinone or/and thymol against monosodium glutamate-induced attention-deficit/hyperactivity disorder (ADHD)-like behavior in …

K Abu-Elfotuh, SA Abdel-Sattar, AN Abbas… - Biomedicine & …, 2022 - Elsevier
Both thymoquinone (TQ) and thymol (T) have been proved to possess a positive impact on
human health. In this research, we aimed to investigate the effect of these compounds …

Adult neurogenesis: a substrate for experience-dependent change

M Opendak, E Gould - Trends in cognitive sciences, 2015 - cell.com
A rapidly growing body of literature indicates that adult neurogenesis in the hippocampus is
sensitive to a variety of environmental factors. The effects of emotionally salient experiences …

Glia: a major player in glutamate–GABA dysregulation‐mediated neurodegeneration

A Sood, K Preeti, V Fernandes… - Journal of …, 2021 - Wiley Online Library
The imbalance between glutamate and γ‐aminobutyric acid (GABA) results in the loss of
synaptic strength leading to neurodegeneration. The dogma on the field considered neurons …

Low-level blast exposure induces chronic vascular remodeling, perivascular astrocytic degeneration and vascular-associated neuroinflammation

MA Gama Sosa, R De Gasperi, D Pryor… - Acta neuropathologica …, 2021 - Springer
Cerebral vascular injury as a consequence of blast-induced traumatic brain injury is
primarily the result of blast wave-induced mechanical disruptions within the neurovascular …