Mechanism and prevention of spiral ganglion neuron degeneration in the cochlea

L Zhang, S Chen, Y Sun - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
Sensorineural hearing loss (SNHL) is one of the most prevalent sensory deficits in humans,
and approximately 360 million people worldwide are affected. The current treatment option …

The role of extracellular Vesicles in the pathogenesis and treatment of rheumatoid arthritis and osteoarthritis

E Bakinowska, K Kiełbowski, A Pawlik - Cells, 2023 - mdpi.com
Cells can communicate with each other through extracellular vesicles (EVs), which are
membrane-bound structures that transport proteins, lipids and nucleic acids. These …

Drug-induced hearing loss: Listening to the latest advances

P Reynard, H Thai-Van - Therapies, 2024 - Elsevier
Sensorineural hearing loss (SNHL) is the most common type of hearing loss. Causes
include degenerative changes in the sensory hair cells, their synapses and/or the cochlear …

Photobiomodulation can enhance stem cell viability in cochlea with auditory neuropathy but does not restore hearing

SY Chang, E Kim, NT Carpena, JH Lee… - Stem Cells …, 2023 - Wiley Online Library
Sensorineural hearing loss is very difficult to treat. Currently, one of the techniques used for
hearing rehabilitation is a cochlear implant that can transform sound into electrical signals …

Chicken utricle stromal cell-derived decellularized extracellular matrix coated nanofibrous scaffolds promote auditory cell production

J Zhang, Y Li, L Liu, R Shen, X Lou - Biomedical Materials, 2023 - iopscience.iop.org
Stem cell therapy has a broad future in treating sensorineural hearing loss in mammals. But
how to produce sufficient functional auditory cells including hair cells, supporting cells as …

Ginsenoside Rc from Panax Ginseng Ameliorates Palmitate-Induced UB/OC-2 Cochlear Cell Injury

NB Gill, PD Dowker-Key, K Hubbard, BH Voy… - International Journal of …, 2023 - mdpi.com
By 2050, at least 700 million people will require hearing therapy while 2.5 billion are
projected to suffer from hearing loss. Sensorineural hearing loss (SNHL) arises from the …

The Protective Effects of Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells in Noise-Induced Hearing Loss of Rats

SY Kim, JE Lee, SH Kang, SM Lee, J Jeon, DR Lee - Cells, 2022 - mdpi.com
A few prior animal studies have suggested the transplantation or protective effects of
mesenchymal stem cells (MSCs) in noise-induced hearing loss. This study intended to …

The Potential of Bone Marrow Derived Mesenchymal Stem Cells in Treating Cisplatin Induced Sensorineural Hearing Loss in a Guinea Pig Animal Model

MHAE Abdelwahed, MH Badreldin, IH Ibrahim… - Tissue and Cell, 2024 - Elsevier
Background Sensorineural hearing loss (SNHL) is the most common sensory deficit
worldwide. Current solutions for SNHL, including hearing aids, cochlear implants, and …

[HTML][HTML] MECOM promotes supporting cell proliferation and differentiation in cochlea

P Chen, N Zuo, C Wu, J Ma, Y Li, J Gu, W Li, S Liu - Journal of Otology, 2022 - Elsevier
Permanent damage to hair cells (HCs) is the leading cause of sensory deafness. Supporting
cells (SCs) are essential in the restoration of hearing in mammals because they can …

Application of new materials in auditory disease treatment

M Li, Y Mu, H Cai, H Wu, Y Ding - Frontiers in cellular neuroscience, 2022 - frontiersin.org
Auditory diseases are disabling public health problems that afflict a significant number of
people worldwide, and they remain largely incurable until now. Driven by continuous …