Systemic candidiasis is an invasive fungal infection caused by members of the genus
Candida. The recent emergence of antifungal drug resistance and increased incidences of …

Surface proteins play a critical role in the interaction between cells and their environment, as
they take part in processes like signaling, adhesion, transport, etc. In pathogenic …

The release of extracellular vesicles (EV) by fungal organisms is considered an alternative
transport mechanism to trans‐cell wall passage of macromolecules. Previous studies have …

Candida albicans fungemia in cancer patients is thought to develop from initial
gastrointestinal (GI) colonization with subsequent translocation into the bloodstream after …

The cell wall proteins of Candida albicans play a key role in morphogenesis and
pathogenesis and might be potential target sites for new specific antifungal drugs. However …

Genome rearrangements resulting in copy number variation (CNV) and loss of
heterozygosity (LOH) are frequently observed during the somatic evolution of cancer and …

ABSTRACT Mycograb (Neu Tec Pharma plc) is a human genetically recombinant antibody
against fungal heat shock protein 90 (HSP90). Antibody to HSP90 is closely associated with …

The pathogenic fungus Candida albicans commonly causes mucosal surface infections. In
immunocompromised patients, C. albicans may penetrate into deeper tissue, enter the …

Cryptococcosis, caused by Cryptococcus neoformans, has been demonstrated to be
controlled by T helper (Th) 1 cells while Th2 cells are associated with fungal growth and …

Systemic candidiasis remains a major cause of disease and death, particularly among
patients suffering from hematological malignancies. In an attempt to contribute to the …