Sperm DNA damage is a useful biomarker for male infertility diagnosis and prediction of
assisted reproduction outcomes. It is associated with reduced fertilization rates, embryo …

Background Reactive oxygen species (ROS) are an array of molecules including oxygen-
centered radicals, which are endowed with one or more unpaired electrons and non-radical …

Assisted reproductive technologies (ARTs) utilize sperm sorting methods to select viable
sperm from the semen samples. Conventional sperm sorting techniques in current use are …

Fertilization and reproduction are central to the survival and propagation of a species.
Couples who cannot reproduce naturally have to undergo in vitro clinical procedures. An …

Male infertility often involves idiopathic or unknown causes, leading to an increasing
demand for assisted reproduction technologies (ART). Conventional sperm sorting …

On the one hand, reactive oxygen species (ROS) are mandatory mediators for essential
cellular functions including the function of germ cells (oocytes and spermatozoa) and …

Sperm cell motility and morphology observed under the bright field microscopy are the only
criteria for selecting a particular sperm cell during Intracytoplasmic Sperm Injection (ICSI) …

Background: Mitochondrial dysfunction has been suggested as a major cause of age-
induced decline in oocyte quality. In the past, donor oocyte cytoplasmic transfer showed …

Purpose The aim of this study was to investigate the most suitable sperm preparation
technique to apply in order to obtain a spermatozoon population with minimal DNA damage …

STUDY QUESTION What are the mechanisms by which the preparation of spermatozoa on
discontinuous density gradients leads to an increase in oxidative DNA damage? SUMMARY …