Brain mechanisms of insomnia: new perspectives on causes and consequences

EJW Van Someren - Physiological reviews, 2021 - journals.physiology.org
While insomnia is the second most common mental disorder, progress in our understanding
of underlying neurobiological mechanisms has been limited. The present review addresses …

Mind-wandering as spontaneous thought: a dynamic framework

K Christoff, ZC Irving, KCR Fox, RN Spreng… - Nature reviews …, 2016 - nature.com
Most research on mind-wandering has characterized it as a mental state with contents that
are task unrelated or stimulus independent. However, the dynamics of mind-wandering …

[HTML][HTML] Trait and state anxiety are mapped differently in the human brain

F Saviola, E Pappaianni, A Monti, A Grecucci… - Scientific reports, 2020 - nature.com
Anxiety is a mental state characterized by an intense sense of tension, worry or
apprehension, relative to something adverse that might happen in the future. Researchers …

From circuits to behaviour in the amygdala

PH Janak, KM Tye - Nature, 2015 - nature.com
The amygdala has long been associated with emotion and motivation, playing an essential
part in processing both fearful and rewarding environmental stimuli. How can a single …

Salience processing and insular cortical function and dysfunction

LQ Uddin - Nature reviews neuroscience, 2015 - nature.com
The brain is constantly bombarded by stimuli, and the relative salience of these inputs
determines which are more likely to capture attention. A brain system known as the'salience …

Resolving the neural circuits of anxiety

GG Calhoon, KM Tye - Nature neuroscience, 2015 - nature.com
Although anxiety disorders represent a major societal problem demanding new therapeutic
targets, these efforts have languished in the absence of a mechanistic understanding of this …

From structure to behavior in basolateral amygdala-hippocampus circuits

Y Yang, JZ Wang - Frontiers in neural circuits, 2017 - frontiersin.org
Emotion influences various cognitive processes, including learning and memory. The
amygdala is specialized for input and processing of emotion, while the hippocampus is …

Large-scale brain networks and psychopathology: a unifying triple network model

V Menon - Trends in cognitive sciences, 2011 - cell.com
The science of large-scale brain networks offers a powerful paradigm for investigating
cognitive and affective dysfunction in psychiatric and neurological disorders. This review …

Divergent routing of positive and negative information from the amygdala during memory retrieval

A Beyeler, P Namburi, GF Glober, C Simonnet… - Neuron, 2016 - cell.com
Although the basolateral amygdala (BLA) is known to play a critical role in the formation of
memories of both positive and negative valence, the coding and routing of valence-related …

Targeting human glucocorticoid receptors in fear learning: a multiscale integrated approach to study functional connectivity

S Battaglia, C Di Fazio, M Mazzà, M Tamietto… - International journal of …, 2024 - mdpi.com
Fear extinction is a phenomenon that involves a gradual reduction in conditioned fear
responses through repeated exposure to fear-inducing cues. Functional brain connectivity …