Clinical effects of curcumin in enhancing cancer therapy: A systematic review

K Mansouri, S Rasoulpoor, A Daneshkhah, S Abolfathi… - BMC cancer, 2020 - Springer
Background Curcumin is herbal compound that has been shown to have anti-cancer effects
in pre-clinical and clinical studies. The anti-cancer effects of curcumin include inhibiting the …

Curcumin-based nanoformulations: A promising adjuvant towards cancer treatment

S Hafez Ghoran, A Calcaterra, M Abbasi, F Taktaz… - Molecules, 2022 - mdpi.com
Throughout the United States, cancer remains the second leading cause of death.
Traditional treatments induce significant medical toxic effects and unpleasant adverse …

Curcumin in cancer therapy: Exploring molecular mechanisms and overcoming clinical challenges

W Wang, M Li, L Wang, L Chen, BC Goh - Cancer Letters, 2023 - Elsevier
Cancer poses a significant global health burden, necessitating the widespread use of
chemotherapy and radiotherapy as conventional frontline interventions. Although targeted …

Mechanism insights of curcumin and its analogues in cancer: An update

P Joshi, K Verma, D Kumar Semwal… - Phytotherapy …, 2023 - Wiley Online Library
Cancer is the world's second leading cause of mortality and one of the major public health
problems. Cancer incidence and mortality rates remain high despite the great …

Curcumin inhibits ovarian cancer progression by regulating circ-PLEKHM3/miR-320a/SMG1 axis

S Sun, H Fang - Journal of Ovarian Research, 2021 - Springer
Background Curcumin has a potential therapeutic role in ovarian cancer. However, whether
curcumin plays anti-cancer role in ovarian cancer by mediating the circular RNA …

Antioxidant curcumin induces oxidative stress to kill tumor cells

Y Hu, L Cheng, S Du, K Wang… - Oncology Letters, 2023 - spandidos-publications.com
Curcumin is a plant polyphenol in turmeric root and a potent antioxidant. It binds to
antioxidant response elements for gene regulation by nuclear factor erythroid 2-related …

Curcumin-human serum albumin nanoparticles decorated with PDL1 binding peptide for targeting PDL1-expressing breast cancer cells

Z Hasanpoor, A Mostafaie, I Nikokar… - International journal of …, 2020 - Elsevier
In this research, programmed death ligand 1 (PDL1) binding peptide was used for targeted
delivery of curcumin to high PDL1-expressing breast cancer cells. Human serum albumin …

Design and various in silico studies of the novel curcumin derivatives as potential candidates against COVID-19-associated main enzymes

H Alici, H Tahtaci, K Demir - Computational biology and chemistry, 2022 - Elsevier
The novel coronavirus disease (COVID-19) is a highly contagious disease caused by the
SARS-CoV-2 virus, leading severe acute respiratory syndrome in patients. Although various …

ST09, a novel curcumin derivative, blocks cell migration by inhibiting matrix metalloproteases in breast cancer cells and inhibits tumor progression in EAC mouse …

S Nirgude, R Mahadeva, J Koroth, S Kumar… - Molecules, 2020 - mdpi.com
Purpose: Curcumin is known for its anticancer and migrastatic activity in various cancers,
including breast cancer. Newer curcumin derivatives are being explored to overcome …

Pardaxin activates excessive mitophagy and mitochondria-mediated apoptosis in human ovarian cancer by inducing reactive oxygen species

YP Chen, PC Shih, CW Feng, CC Wu, KH Tsui, YH Lin… - Antioxidants, 2021 - mdpi.com
Most ovarian cancer (OC) patients are diagnosed with stage III or higher disease, resulting
in a poor prognosis. Currently, paclitaxel combined with carboplatin shows the best …