Background and Objectives: It is generally accepted that inflammatory cells found in the
tumor microenvironment are involved in the neoplastic process, promoting cell proliferation …

Abstract Changes in reactive oxygen species (ROS) levels affect many aspects of cell
behavior. During carcinogenesis, moderate ROS production modifies gene expression to …

While cancer remains a significant global health problem, advances in cancer biology, deep
understanding of its underlaying mechanism and identification of specific molecular targets …

Incidence of cutaneous squamous cell carcinoma (cSCC) and actinic keratosis has
increased worldwide, and non-steroidal anti-inflammatory drugs as celecoxib are …

In the present study, we constructed the recombinant plasmid IL10-PEGFP-C1 and
successfully transfected into human mesenchymal stem cells. After culturing for 72 h, the …

Colorectal cancer (CRC) is a major cause of morbidity and mortality worldwide. Despite the
critical involvement of epigenetic modifications in CRC, the studies on the chemotherapeutic …

Abstract Cyclooxygenase-2 (COX-2) is expressed in a variety of human colorectal cancer
cells and can contribute to carcinogenesis. This study aimed to investigate the effect of …

Background Prostate cancer is the most common type of cancer among men. Studies
showed that the regular use of nonsteroidal antiinflammatory drugs might reduce disease …

Purpose: To evaluate the effect of a topical nonsteroidal anti-inflammatory drug (0.1%
pranoprofen) on the expression of VEGF and Cox-2 in primary pterygium. Methods: This was …

Few studies have reported on the analyses of drugs targeting enriched populations of
cancer stem cells (CSCs) as a means for identifying potent anti-CSC agents. This review …