Singlet oxygen (1O2) is a biologically relevant reactive oxygen species capable of efficiently
reacting with cellular constituents. The resulting oxidatively generated damage to nucleic …

Endogenous and exogenous sources cause free radical-induced DNA damage in living
organisms by a variety of mechanisms. The highly reactive hydroxyl radical reacts with the …

In this survey, emphasis was placed on the main photoreactions of nucleic acid components,
involving both direct and indirect effects. The main UVB-and UVA-induced DNA …

Oxidatively induced DNA damage is caused in living organisms by endogenous and
exogenous reactive species. DNA lesions resulting from this type of damage are mutagenic …

Endogenous and exogenous sources cause oxidatively induced DNA damage in living
organisms by a variety of mechanisms. The resulting DNA lesions are mutagenic and …

Deoxyribonucleic acid (DNA) appears to be a critical cellular target for the biological effects
(cellular lethality, mutagenesis, carcinogenesis, and ageing) of oxidation processes …

The aim of the present work was to evaluate the potential for 1 O 2 to induce oxidation of
cellular DNA. For this purpose cells were incubated in the presence of a water-soluble …

Use of one-electron oxidants such as Na2IrCl6 to oxidize 8-oxo-7, 8-dihydro-2 '-
deoxyguanosine (OG) residues in oligodeoxynucleotides was previously shown to lead to …

Reactive oxygen species (ROS) are harnessed by the cell for signaling at the same time as
being detrimental to cellular components such as DNA. The genome and transcriptome …

This survey focuses on recent aspects of the singlet oxygen oxidation of the guanine moiety
of nucleosides, oligonucleotides, isolated and cellular DNA that has been shown to be the …