Exploration of natural flavones' bioactivity and bioavailability in chronic inflammation induced-type-2 diabetes mellitus
L Miao, C Liu, MS Cheong, R Zhong, Y Tan… - Critical Reviews in …, 2023 - Taylor & Francis
Diabetes, being the most widespread illness, poses a serious threat to global public health.
It seems that inflammation plays a critical role in the pathophysiology of diabetes. This …
It seems that inflammation plays a critical role in the pathophysiology of diabetes. This …
Bile salt stabilized nanovesicles as a promising drug delivery technology: A general overview and future perspectives
R Abdel-moneum, RS Abdel-Rashid - Journal of Drug Delivery Science …, 2023 - Elsevier
Bile salts stabilized nanovesicles (bilosomes) have received tremendous attention in the
previous decade due to their vast preferabilities as well as the flexibility of their modification …
previous decade due to their vast preferabilities as well as the flexibility of their modification …
Development and optimization of curcumin analog nano-bilosomes using 21.31 full factorial design for anti-tumor profiles improvement in human hepatocellular …
H Abbas, YA El-Feky, MM Al-Sawahli, NM El-Deeb… - Drug Delivery, 2022 - Taylor & Francis
Curcumin (CU) is a natural polyphenolic phytoingredient. CU has anti-inflammatory, anti-
oxidant, and anticancer activities. The poor solubility, bioavailability, and stability of CU …
oxidant, and anticancer activities. The poor solubility, bioavailability, and stability of CU …
Evaluation of metformin hydrochloride tailoring bilosomes as an effective transdermal nanocarrier
Introduction Metformin hydrochloride (metformin HCL), a first-line drug treating diabetes type
II, was known to cause severe gastritis, so seeking a non-oral dosage form was the new …
II, was known to cause severe gastritis, so seeking a non-oral dosage form was the new …
TPGS surface modified bilosomes as boosting cytotoxic oral delivery systems of curcumin against doxorubicin resistant MCF-7 breast cancer cells
The goal of this work was to design nude bilosomes (Bil) and D-alpha-tocopheryl
polyethylene glycol succinate (TPGS) surface coated bilosomes as an oral delivery platform …
polyethylene glycol succinate (TPGS) surface coated bilosomes as an oral delivery platform …
Hyaluronic acid-enriched bilosomes: an approach to enhance ocular delivery of agomelatine via D-optimal design: formulation, in vitro characterization, and in vivo …
AA Nemr, GM El-Mahrouk, HA Badie - Drug delivery, 2022 - Taylor & Francis
Agomelatine (AGO) is a dual-functional drug. It uses as an antidepressant when orally
administrated and antiglaucomic when topically applied to the eye. This study aimed to …
administrated and antiglaucomic when topically applied to the eye. This study aimed to …
Novel bile salt stabilized vesicles-mediated effective topical delivery of diclofenac sodium: A new therapeutic approach for pain and inflammation
The oral delivery of diclofenac sodium (DNa), a non-steroidal analgesic, anti-inflammatory
drug, is associated with various gastrointestinal side effects. The aim of the research was to …
drug, is associated with various gastrointestinal side effects. The aim of the research was to …
Development and optimization of transethosomal gel of apigenin for topical delivery: In-vitro, ex-vivo and cell line assessment
The main aim of this study was to optimize the transethosomes of apigenin formulated by the
thin film hydration method using surfactant Span 80. Response surface Box-Behnken design …
thin film hydration method using surfactant Span 80. Response surface Box-Behnken design …
A brain-targeted approach to ameliorate memory disorders in a sporadic Alzheimer's disease mouse model via intranasal luteolin-loaded nanobilosomes
MA Elsheikh, YA El-Feky, MM Al-Sawahli, ME Ali… - Pharmaceutics, 2022 - mdpi.com
Impaired memory and cognitive function are the main features of Alzheimer's disease (AD).
Unfortunately, currently available treatments cannot cure or delay AD progression …
Unfortunately, currently available treatments cannot cure or delay AD progression …
Formulation and evaluation of topical nano-lipid-based delivery of butenafine: in vitro characterization and antifungal activity
A Zafar, SS Imam, NK Alruwaili, M Yasir, OA Alsaidan… - Gels, 2022 - mdpi.com
The present research work was designed to prepare butenafine (BN)-loaded bilosomes
(BSs) by the thin-film hydration method. BN is a sparingly water-soluble drug having low …
(BSs) by the thin-film hydration method. BN is a sparingly water-soluble drug having low …