Primary effusion lymphoma (PEL) is a rare and aggressive disease, affecting a unique
population of patients who are often elderly or immunocompromised. PEL is associated with …

Kaposi's sarcoma-associated herpesvirus (KSHV) also known as human herpesvirus 8
(HHV-8), is linked to several human malignancies including Kaposi sarcoma (KS), primary …

Hippo signaling is modulated in response to cell density, external mechanical forces, and
rigidity of the extracellular matrix (ECM). The Mps one binder kinase activator (MOB) adaptor …

The ongoing chronic inflammation and subsequent fibrosis play an important role in
ligamentum flavum (LF) fibrosis and hypertrophy in patients with lumbar spinal canal …

Angiogenesis is critical for the initiation and progression of solid tumors, as well as
hematological malignancies. While angiogenesis in solid tumors has been well …

Tumor development is closely related to angiogenesis, and VEGFR2 plays an important role
in tumor angiogenesis. It is broadly expressed in the blood vessels, especially in the …

Cholangiocarcinoma (CCA) is a unique liver cancer subtype with an increasing incidence
globally. The lack of specific symptoms and definite diagnostic markers results in a delayed …

Primary effusion lymphoma (PEL) is a malignant B-cell lymphoma attributable to Kaposi
sarcoma-associated herpesvirus (KSHV) infection. PEL is characterized by invasive …

PEL is an aggressive mature B-cell neoplasm primarily seen in young to middle aged men
with HIV, though immunosuppression related to age and comorbidities such as cirrhosis or …

Radioimmunotherapy (RIT) is a therapy that combines a radioactive nucleotide with a
monoclonal antibody (mAb). RIT enhances the therapeutic effect of mAb and reduces toxicity …