The therapeutic use of messenger RNA (mRNA) has fueled great hope to combat a wide
range of incurable diseases. Recent rapid advances in biotechnology and molecular …

Objective To compare the efficacy of covid-19 vaccines between immunocompromised and
immunocompetent people. Design Systematic review and meta-analysis. Data sources …

Up to 50% of the people who have died from COVID-19 had metabolic and vascular
disorders. Notably, there are many direct links between COVID-19 and the metabolic and …

Background Available data show that COVID-19 vaccines may be less effective in
immunocompromised populations, who are at increased risk of severe COVID-19 …

COVID-19 vaccinations are essential to mitigate the pandemic and prevent severe SARS-
CoV-2 infections. However, the serum antibody levels in vaccinated individuals gradually …

The COVID-19 pandemic has profound adverse effects on the population on dialysis.
Patients requiring dialysis are at an increased risk of SARS-CoV-2 infection and mortality …

Importance Fewer than 50% of kidney transplant recipients (KTRs) develop antibodies
against the SARS-CoV-2 spike protein after 2 doses of an mRNA vaccine. Preliminary data …

Background Disease-specific studies have reported impaired humoral responses after
SARS-CoV-2 vaccination in patients with immune-mediated inflammatory disorders treated …

Vaccine-mediated immunity often relies on the generation of protective antibodies and
memory B cells, which commonly stem from germinal center (GC) reactions. An in-depth …

Importance Recipients of solid organ transplant (SOT) experience decreased
immunogenicity after COVID-19 vaccination. Objective To summarize current evidence on …